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[EXPIRED] The Capital Region of Copenhagen is looking for a Postdoctoral / Research fellow in advanced 7T MRI and MRS neuroscience applications

If you are a team-oriented MR researcher eager to unleash the full potentials of 7T ultra-high field MRI and MRS through novel software and hardware solutions, then you might be the person we are looking for!

As a researcher at the Danish Research Centre for Magnetic Resonance (DRCMR) you will support new and ongoing 7T studies and have the freedom to develop novel MRI/MRS sequences, hardware and processing methods primarily targeting neuroscientific applications.

You will be working closely with a multidisciplinary team of engineers, physicists, biomedical and clinical experts, who are developing and applying exciting and cutting-edge microstructural and X-nuclei imaging techniques for 7T. You will be part of the Ultra-high field MR group (www.drcmr.dk/7t). We have a Philips 7T research only scanner with 2- and 8-channel transmit, 32 receive and 64 shim channels in addition to the standard 3rd order shim.

DRCMR is one of the leading research centers for biomedical MRI in Europe (www.drcmr.dk). Our interdisciplinary research is geared to triangulate between MR physics, basic physiology, and clinical research. Approximately 70 researchers from a diverse range of disciplines work together to pursue basic and clinically applied MR research with a focus on structural, functional, and metabolic MRI of the human brain and its disorders. Collaboration is key at DRCMR – we do not expect any researcher to be able to do everything alone, but we expect everyone to be interested in sharing knowledge with colleagues.

The DRCMR is embedded in the Department of Radiology and Nuclear Medicine, a large diagnostic imaging department including all biomedical imaging modalities at Copenhagen University Hospital Hvidovre. The hospital also has strong collaborative links with the Technical University of Denmark and is part of the newly established organizational framework, The Technical University Hospital of Greater Copenhagen. DRCMR has close interaction with clinicians and radiologists and a state-of-the-art MR-research infrastructure, which includes a pre-clinical 7T MR scanner, six whole-body MR scanners (one 7T, four 3T and one 1.5T scanners), a hardware workshop and laboratory, a neuropsychology laboratory, an EEG laboratory, and two laboratories for non-invasive brain stimulation.  The 7T is a national research infrastructure, serving internal and external users across Denmark.

Your profile:

You are a team-oriented, creative and enthusiastic researcher with:

  • A PhD degree in engineering, physics, biomedical sciences or a related field.
  • At least 2-3 years of doctoral and/or postdoctoral experience within ultra-high field MRI (preferably on Philips systems).
  • A clear interest in MRI/MRS acquisition, reconstruction and image analysis.
  • Excellent knowledge of MR physics and programming skills in C/C++, MATLAB or Python.
  • Ideally experience in MR sequence programming (preferably on Philips MR system).
  • Affinity with medical applications.
  • Strong communication and collaborative skills.

Your tasks:

  • To work directly with other scientists to ensure that our research studies take full advantage of the 7T MR scanner by maximizing the clinical information available in the multi-parametric MRI images (structural, functional and other quantitative read-outs) and MRS including deuterium spectroscopy.
  • Assist with the daily operations of the 7T scanners, which encompasses tasks such as conducting MRI safety trainings and quality control of scanner performance.
  • To develop novel sequences and data analysis methods, and possibly new hardware designs.
  • To advance the field through your own research.
  • To engage in internal education, grant writing, knowledge dissemination, and publication of results in international, recognized scientific journals.

Your position:

You will be employed for a four-year period at the DRCMR and join the ultra-high field MR group.

 

Selected Publications

Gaist, D., Hougaard, A., Garde, E., Reislev, N. L., Wiwie, R., Iversen, P., Madsen, C. G., Blaabjerg, M., Nielsen, H. H., Krøigård, T., Østergaard, K., Kyvik, K. O., Hjelmborg, J., Madsen, K., Siebner, H. R. & Ashina, M.
Migraine with visual aura associated with thicker visual cortex.
Brain. 141, 3, p. 776-785, 2018.

Dogonowski, A. M., Andersen, K. W., Sellebjerg, F., Schreiber, K., Madsen, K. H. & Siebner, H. R.
Functional neuroimaging of recovery from motor conversion disorder: A case report.
NeuroImage.

Larsen, K. M., Pellegrino , G., Birknow, M. R., Kjær , T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, T., Mørup, M. & Siebner, H. R.
22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response.
Schizophrenia Bulletin. 44, 2, p. 388-397, 2018.

Larsen, K. M., Dzafic, I., Siebner, H. R. & Garrido, M. I.
Alteration of functional brain architecture in 22q11.2 deletion syndrome - Insights into susceptibility for psychosis.
NeuroImage.

Macoveanu, J., Baaré, W., Madsen, K. H., Kessing, L. V., Siebner, H. R. & Vinberg, M.
Risk for affective disorders is associated with greater prefrontal gray matter volumes: A prospective longitudinal study.
NeuroImage. Clinical. 17, p. 786-793, 2018.

van der Kleij, L. A., Petersen, E. T., Siebner, H. R., Hendrikse, J., Frederiksen, K. S., Sobol, N. A., Hasselbalch, S. G. & Garde, E.
The effect of physical exercise on cerebral blood flow in Alzheimer's disease.
NeuroImage: Clinical. 20, p. 650-654, 2018.

Ammitzbøll, C., Dyrby, T. B., Lyksborg, M., Schreiber, K., Ratzer, R., Romme Christensen, J., Iversen, P., Magyari, M., Garde, E., Sørensen, P. S., Siebner, H. R. & Sellebjerg, F.
Disability in progressive MS is associated with T2 lesion changes.
Multiple Sclerosis and Related Disorders. 20, p. 73-77, 2017.

Lundell, H., Svolgaard, O., Dogonowski, A-M., Romme Christensen, J., Selleberg, F., Soelberg Sørensen, P., Blinkenberg, M., Siebner, H. R. & Garde, E.
Spinal cord atrophy in anterior-posterior direction reflects impairment in multiple sclerosis.
Acta Neurologica Scandinavica. 136, 4, p. 330-337, 2017.

Miskowiak, K. W., Macoveanu, J., Jørgensen, M. B., Støttrup, M. M., Ott, C. V., Jensen, H. M., Jørgensen, A., Harmer, J., Paulson, O. B., Kessing, L. V. & Siebner, H. R. Neural Response After a Single ECT Session During Retrieval of Emotional Self-Referent Words in Depression: A Randomized, Sham-Controlled fMRI Study. International Journal of Neuropsychopharmacology. 21, 3, p. 226-235, 2017.

Fisher, P. M., Larsen, C. B., Beliveau, V., Henningsson, S., Pinborg, A., Holst, K. K., Jensen, P. S., Svarer, C., Siebner, H. R., Knudsen, G. M. & Frokjaer, V. G. Pharmacologically Induced Sex-Hormone Fluctuation Effects on Resting-State Functional Connectivity in a Risk Model for Depression: A Randomised Trial. Neuropsychopharmacology. 42, 2, p. 446-453, 2017.

Dogonowski, A.M., Blinkenberg, M., Paulsonm O.B., Sellebjergm F., Sørensen, P.S., Siebner, H.R., Madsen, K.H. Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis. J Neurol Neurosurg Psychiatry 87, 8, p. 912-914, 2016. 

Gaist, D., Garde, E., Blaabjerg, M., Nielsen, H.H., Krøigård, T., Østergaard, K., Møller, H.S., Hjelmborg, J., Madsen, C.G., Iversen, P., Kyvik, K.O., Siebner, H.R., Ashina, M. Migraine with aura and risk of silent brain infarcts and white matter hyperintensities: an MRI study. Brain. 139, 7, 2015-2023, 2016.

Gelskov, S.V., Madsen, K.H., Ramsøy, T.Z., Siebner, H.R. Aberrant neural signatures of decision-making: Pathological gamblers display cortico-striatal hypersensitivity to extreme gambles. Neuroimage. 128, 342-352, 2016.

Herz, D.M., B.N. Haagensen, M.S. Christensen, et al. Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain 138, p. 1658-1666, 2015.

Løkkegaard, A., Herz, D.M., Haagensen, B.N., Lorentzen, A.K., Eickhoff, S.B., Siebner, H.R. Altered sensorimotor activation patterns in idiopathic dystonia-an activation likelihood estimation meta-analysis of functional brain imaging studies. Hum Brain Mapp. 37, 2, p. 547-557, 2016.

Macoveanu, J., Miskowiak, K., Kessing, L.V., Vinberg, M., Siebner, H.R. Healthy co-twins of patients with affective disorders show reduced risk-related activation of the insula during a monetary gambling task. J Psychiatry Neurosci. 41, 1, p. 38-47, 2016.

 

Coordinator

Hartwig R. Siebner

Coordinator

Mads Alexander Just Madsen