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Computational and Systems Neuroscience

Computational and Systems Neuroscience Billede1

Our research groups are organised into different research areas.

 

In this research area, we focus on Computational & Systems Neuroscience. This means applying computational models to neural data at the systems level.

Brain-Body-Interaction: We investigate how the brain and body communicate to regulate physiological states and behaviour. Using advanced neuroimaging and computational models, we study how bodily signals shape brain activity, perception, and decision-making.  

Hartwig Siebner Group Leader: Hartwig Siebner

Computational Neuroscience of Reward: We study how the human brain learns from rewards and punishments, and how motivation and decision-making are guided by reward signals. Our work combines behavioural tasks, fMRI, and computational modeling to uncover the neural basis of reward processing.

Oliver Hulme Group Leader: Oliver Hulme

Cortico-Basal Ganglia Interactions: We explore the computations performed by cortico-basal ganglia circuits. Our research examines how these networks support learning, action selection, and decision-making, bridging insights from systems neuroscience and computational theory.

Mattias Rickhag portræt 255x343 Group Leader: Mattias Rickhag

Movement Disorders: We investigate the neural mechanisms underlying Parkinson's disease and other movement disorders. By combining patient studies, imaging, and modeling, we aim to understand how circuit dysfunction gives rise to symptoms, and to develop better diagnostic and therapeutic approaches.

David Meder portræt 255x343 Group Leader: David Meder  

Control of Movement: We study how the brain controls skilled movement. Using behavioural experiments, brain stimulation and neuroimaging, we uncover how neural circuits coordinate motor commands, adapt to changes, and support flexible actions.

Lasse Christiansen portræt 255x343 Group Leader: Lasse Christiansen

 

Join us!

We have lots of opportunities for you as interns, research assistants, masters, PhDs.

E-mail the Group Leader you are most interested in or send general enquiries to .

Staff April 2025

 

 

Selected Publications

Michel Lange, V., Messerschmidt, M., Harder, P., Siebner, H. R. & Boye, K. Planning and production of grammatical and lexical verbs in multi-word messages. P L o S One. 12, 11 2017.

*Meder, D., *Haagensen, B., Hulme, O.J., Morville, T.M., Gelskov, S., Herz, D., Diomsina, B., Christensen, M., Madsen, K.M., Siebner, H.R., Tuning the Brake While Raising the Stake: Network Dynamics During Sequential Decision-Making Journal of Neuroscience

Herz, D.M., Christensen, M.S., Bruggemann, N., Hulme, O. J., Ridderinkhof, R.K., Madsen, K.H., Siebner, H.R.,(2014) Motivational tuning of fronto-subthalamic connectivity facilitates control of action impulses. Journal of Neuroscience

Meder, D., Madsen, K.M., Hulme, O.J., Siebner, H.R., Chasing probabilities – Signalling negative and positive prediction errors across domains. Neuroimage

Hulme,O.J., Skov, M., Chadwick M., Siebner, H.R., Ramsøy, T.Z.(2014) Sparse encoding of Associative Density in the Hippocampus Neuroimage

Coordinator

Oliver Hulme

Coordinator