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Brain Stimulation

Transcranial Brain Stimulation (TBS) can influence the ongoing electrical activity of the human brain.

A range of complementary TBS techniques can be used to interact with brain activity without discomfort: Transcranial Magnetic Stimulation (TMS) produces a rapidly changing electromagnetic field in a stimulation coil that is placed on the head. This electromagnetic field induces an electrical filed in the part of the brain that is close to the coil that can induce action potentials in cortical neurons. Transcranial Current Stimulation (TCS) directly applies weak electric fields with the help of electrodes that are attached on the skin. TCS indices a weak current in the brain that modulates ongoing brain activity, but TCS does not elicit action potentials.

Transcranial Brain Stimulation (TBS) is a versatile neuroscientific and therapeutic tool since it can be used to identify and evaluate electrophysiological markers and it can influence brain activity, even beyond the duration of stimulation.

The Transcranial Brain Stimulation (TBS) group is a method group led by Postdoc Lasse Christiansen. Its aim is to facilitate, support and advance all forms of transcranial brain stimulation at DRCMR. Activities of the group range from improving state-of-the-art protocols for different TBS techniques to educating DRCMR researchers and students and by ensuring the highest technical and safety standards in all laboratories. The grup meets every second Monday at 10am and welcomes all researchers at DRCMR who wish to use TBS as a scientific tool.

Teaching activities:

  • Yearly international workshop on Non-invasive Transcranial Brain Stimulation (for information about the upcoming NTBS workshop in November 2019, click here. For information about the latest NTBS workshop held in November 2018, click here)

Research activities:

The group actively supports all TMS related research projects. Two areas form the present focus of interest:

  • Mapping and shaping functional representations in human brain networks with TBS
  • Improving the efficacy and reproducibility of current TBS protocols 
  • Identifying both central and peripheral, unintended effects of TBS.

Selected Publications

Conde, V., Tomasevic, L., Akopian, I., Stanek, K., Saturnino, GB., Thielscher, A., Bergmann, TO., & Siebner, HR.: The non-transcranial TMS-evoked potential is an inherent source of ambiguity in TMS-EEG studies. Neuroimage 2019, 185, 300-312.

Raffin, E., & Siebner, HR.: Use-dependent plasticity in human primary motor hand area:synergistic interplay between trainng and immobilization. Cerebral Cortex 2018, 29(1), 356-371.

Dubbioso, R., Raffin, E., Karabanov, A., Thielscher, A., & Siebner, HR.: (2017) Centre-surround organization of fast sensorimotor integration in human motor hand area. Neuroimage, 2017, 158, 37-47.

Raffin E, Pellegrino G, Di Lazzaro V, Thielscher A, Siebner HR: Bringing transcranial mapping into shape: Sulcus-aligned mapping captures motor somatotopy in human primary motor hand area. Neuroimage. 2015;120:164-

Karabanov AN, Ziemann U, Hamada M, George MS, Quartarone A, Classen J, Massimini M, Rothwell J, Siebner HR (2015) Probing Homeostatic Plasticity of Human Cortex With Non-invasive Transcranial Brain Stimulation. Vol. 8(3) p. 442-54

News & Events

Group Members

Lasse Christiansen

Group Leader

Leo Tomasevic

Angela Mastropasqua

Show all group members (7)

External Collaborators

Estelle Raffin

Grenoble, France

Assoc. Prof. Angelo Quartarone 

Università Degli Studi Di Messina, Italy