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[EXPIRED] The Capital Region of Copenhagen is looking for a PhD candidate in Machine Learning for Neuronal Feature Identification in 3D Microscopic Imaging - DTU Compute

Do you want to join a multidisciplinary team working with a new 3D optical imaging technology and develop machine learning models to map in the brain neuronal and cellular objects, their geometry, density and organization? Are you interested in learning about 3D imaging analysis, brain anatomy, collect your own high-quality microscopic data as well as generating synthetic cellular environments to evaluate and train your model? Are you intrigued by solving challenges working with big data? Are you eager to develop innovative solutions in a groundbreaking project at the intersection of neuroimaging and machine learning? If yes, we encourage you to apply and join our team!

DTU Compute’s Section for Visual Computing is opening a PhD position in Machine Learning for Neuronal Feature Identification in 3D Microscopic Imaging. The project is financed by the Independent Research Fund Denmark – and aims at modelling neuronal anatomical compartments from 3D Light-Sheet (label-free- and fluorescence- based) microscopic imaging data. The project will also be carried out at the Danish Research Centre for MR at Copenhagen University Hospital Hvidovre, and in collaboration with IRB Barcelona: Institute for Research in Biomedicine (Barcelona, Spain).

Qualifications

  • Master's degree in visual computing, computational science and engineering, or equivalent, with focus on machine learning,
  • Experience in Python programming is highly desired,
  • Practical experience working with Machine Learning within the image processing and analysis field will be a plus,
  • Experience in experimental bioimaging will be highly valued: Interest in data collection, understanding of image data quality concepts for ensuring optimal modelling purposes. 
  • Interest in learning light-sheet based physics underpinning microscopic image contrast to be modelled, 
  • You have a good team spirit, innovative and constructive thinking, research excitement. Good English communication skills are essential.

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment 
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

You can read more about the Microstructure and Plasticity group you be part of, the Visual Computing section and the Department of Applied Mathematics and Computer Science at DTU as well as the Danish Research Centre for MR.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. 


DTU Compute has a total staff of 400 including 100 faculty members and 130 Ph.D. students. We offer introductory courses in mathematics, statistics, and computer science to all engineering programmes at DTU and specialised courses to the mathematics, computer science, and other programmes. We offer continuing education courses and scientific advice within our research disciplines and provide a portfolio of innovation activities for students and employees.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

 

Recent Publications

Beha GH, Stemmerik MG, Boer VO, van der Ploeg AT, van der Beek NAME, Andersen H, Marsman A, Jacobsen LN, Theunissen MTM, Petersen ET, Vissing J. 2025. Quantification of muscle glycogen distribution in Pompe disease using 7 Tesla 13C NMR spectroscopy. JNNP. Accepted.

Güler S, Zivkovic I, Boer VO, Zhurbenko V, Petersen ET. 2025. The mode of operation of high-impedance coils and shielded coaxial cable coils: A comparative study. NMR Biomed. 38(8): e70071. https://doi.org/10.1002/nbm.70071

London A, Schaufuss A, Povazan M, Dichman M-L, Merhout J, Dirksen C, Madsbad S, Siebner HR, Lundsgaard A, Fritzen AM, Kiens B, Bojsen-Møller KN. 2025. Effects of acute iso- and hypocaloric carbohydrate restriction on liver fat and glucose and lipid metabolism. J Clin Endocrinol Metab. dgaf382, https://doi.org/10.1210/clinem/dgaf382

Güler S, Povazan M, Zhurbenko V, Zivkovic I. 2025. An 8Tx/32Rx head-neck coil at 7T by combining 2Tx/32Rx Noval coil with 6TRx shielded coaxial cable elements. Magn Reson Med. 93(2): 864-872. https://doi.org/10.1002/mrm.30297

Madelung CF, Løkkegaard A, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Hejl A-M, Meder D, Siebner HR. 2025. High-resolution mapping of substantia nigra in Parkinson’s disease using 7 tesla magnetic resonance imaging. Npj Parkinsons Dis. 11(113). https://doi.org/10.1038/s41531-025-00972-7

London A, Richter MM, Sjøberg KA, Wewer Albrechtsen NJ, Povazan M, Drici L, Schaufuss A, Madsen L, Øyen J, Madsbad S, Juul Holst J, van Hall G, Siebner HR, Richter EA, Kiens B, Lundsgaard A, Bojsen-Møller KN. 2024. The impact of short-term eucaloric low- and high-carbohydrate diets on liver triacylglycersol content in males with overweight and obesity: a randomized crossover study. Am J Clin Nutrition. 120(2): 283-293. https://doi.org/10.1016/j.ajcnut.2024.06.006

Madsen MAJ, Povazan M, Wiggermann V, Lundell H, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2024. Association of cortical lesions with regional glutamate, GABA, N-Acetylaspartate, and Myoinositol levels in patients with multiple sclerosis. Neurology. 103(1): e209543. https://doi.org/10.1212/WNL.0000000000209543

Stærkind H, Jensen K, Müller JH, Boer VO, Polzik ES, Petersen ET. 2024. High-field optical cesium magnetometer for magnetic resonance imaging. PRX Quantum. 5(2): 020320. https://doi.org/10.1103/PRXQuantum.5.020320

Stærkind H, Jensen K, Müller JH, Boer VO, Petersen ET, Polzik ES. 2023. Precision measurement of the excited state Landé g-factor and diamagnetic shift of the Cesium D2 line. Phys Rev X. 13(2): 021036. https://doi.org/10.1103/PhysRevX.13.021036

Boer VO, Pedersen JO, Arango N, Kuang I, Stockmann J, Petersen ET. 2022. Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field. MAGMA. 35(6): 943-951. https://doi.org/10.1007/s10334-022-01014-6

Andersen M, Laustsen M, Boer V. Accuracy investigations for volumetric head-motion navigators with and without EPI at 7 T. 2022. Magn Reson Med. 88(3): 1198-1211. https://doi.org/10.1002/mrm.29296

Madsen MAJ, Wiggermann V, Marques MFM, Lundell H, Cerri S, Puonti O, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2022. Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study. Brain. 145(10): 3522-3535. https://doi.org/10.1093/brain/awac203

Sandström KO, Baltzersen OB, Marsman A, Lemvigh CK, Boer VO, Bojesen KB, Nielsen MØ, Lundell H, Sulaiman DK, Sørensen ME, Fagerlund B, Lahti AC, Syeda WT, Pantelis C, Petersen ET, Glenthøj BY, Siebner HR, Ebdrup BH. 2022. Add-on memantine to dopamine antagonism to improve negative symptoms at first psychosis – the AMEND trial protocol. Front Psychiatry. 13: 889572. https://doi.org/10.3389/fpsyt.2022.889572

Madelung CF, Meder D, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Petersen ET, Hejl A-M, Løkkegaard A, Siebner HR. 2022. Locus coeruleus shows a spatial pattern of structural disintegration in Parkinson’s disease. Movement Disord. 37(3): 479-489. https://doi.org/10.1002/mds.28945

 

Selected Recent Conference Abstracts

Engel K, Wiggermann V, Ronen I, Lundell H. Correction of phase fluctuations in diffusion-weighted MRS at high b-values with external phantom reference. ISMRM annual meeting. 05/2025,

Madsen MAJ, Christiansen L, Povazan M, Wiggermann V, Siebner HR. Regional glutamate but not GABA concentration scales with TMS-based measures of cortical excitability – a combined 7T MR spectroscopy and TMS study of the human primary motor hand area. Brain Stimulation, Kyoto, Japan, 02/2025 [Brain Stimulation 18(1) 576, 2025]

Madsen MAJ, Wiggermann V, Lundell H, Christiansen L, Romme Christensen J, Blinkenberg M, Sellebjerg F, Siebner HR. The impact of pathway-specific cortical and white matter pathology on trans-callosal conduction and inhibition in multiple sclerosis, ECTRIMS, Copemhagen, Denmark, 09/2024

Madsen MAJ, Wiggermann V, Christiansen L, Povazan M, Lundell H, Puonti O, Romme Christensen J, Sellebjerg F, Siebner HR. The ipsilateral silent period and its link to cortical lesions in multiple sclerosis, Brain Stimulation, Lisbon, Portugal, 02/2023, [Brain Stimulation 14(6) 1628, 2023]

Stemmerik M, Beha G, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Using high-field magnetic resonance spectroscopy to measure muscle glycogen in patients with McArdle disease. Neuromuscular Disorders. 32. S73-S74.

Beha G, Stemmerik M, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Quantification of glycogen distribution in late-onset Pompe patients using 7 Tesla C13 NMR spectroscopy. Neuromuscular Disorders. 32. S73.

Madsen MAJ, Wiggermann V, Povazan M, Lundell H, Boer VO, Marsman A, Blinkenberg MB, Romme Christensen J, Sellebjerg FT, Siebner HR. 2022. Linking cortical demyelination to changes in brain metabolism in multiple sclerosis: a 7T MR spectroscopy study. ECTRIMS annual (virtual) meeting.

Güler S, Costa G, Boer V, Paulides M, Baltus P, Petersen E, Zivkovic I. 2022. Shielded coaxial cable coils: the array configuration for maximized central SNR at 7T MRI. Joint Annual Meeting ISMRM-ESMRMB, 31st annual ISMRM meeting.

Güler S, Zhurbenko V, Zivkovic I, Boer V, Petersen ET. 2022. Second resonance mode ensure intrinsic low coupling between elements on shielded-coaxial-cable coil designs. Joint Annual Meeting ISMRM-ESMRMB, 31st annual ISMRM meeting.

Group Members

Vanessa Wiggermann

Group Leader

Henrik Lundell

Group Leader

Lars G. Hanson

Sebastian Ladegaard Storm

Paul Wessel de Bruin

Ahmed Ibrahim Al-Rahimi

Show all group members (22)

External Collaborators

Jeroen Hendrikse

Department of Radiology, University Medical Center Utrecht, The Netherlands


Dennis Klomp

Department of Radiology, University Medical Center Utrecht, The Netherlands


Andrew Webb

Department of Radiology, Leiden University Medical Center, The Netherlands


Matthias van Osch

Department of Radiology, Leiden University Medical Center, The Netherlands


Itamar Ronen

Department of Radiology, Leiden University Medical Center, The Netherlands


Karin Markenroth Bloch

Swedish National 7T facility, Lund, Sweden


Gunther Helms

Swedish National 7T MRI Facility, Medical Radiation Physics, Lund, Sweden


Kirsten Borup Bojesen

Center for Neuropsychiatric Schizophrenia Research, Mental Health Services, Capital Region of Denmark, Denmark