[EXPIRED] The Capital Region of Copenhagen is looking for a postdoctoral researcher in brain imaging informed transcranial stimulation

4-year postdoctoral research position in brain imaging informed transcranial stimulation at DRCMR

We are currently scaling up our efforts to develop novel circuit-based precision brain stimulation approaches of the human brain.
Our long-term goal is to enhance the efficacy of transcranial stimulation as a treatment of neurological and psychiatric diseases.

We are looking for a postdoctoral researcher who
● is experienced in transcranial brain stimulation,
● enjoys working at the intersection of engineering, neurophysiology, brain mapping, and clinical neuroscience
● is eager to advance state-dependent precision stimulation to modulate brain networks and improve brain network dysfunction.

You will become part of a transdisciplinary team focusing on developing precision brain stimulation therapy by combining transcranial magnetic stimulation with neuroimaging. You will work alongside dedicated researchers at our recently established interventional brain stimulation research facility comprising three state-of-the-art brain stimulation laboratories fully equipped with robotic transcranial brain stimulation, neuronavigation, and EEG.

What we do: We are conducting state-of-the-art neuroimaging-informed brain stimulation therapy in Parkinson’s disease, Multiple Sclerosis, and Major Depressive Disorder. We are a world leading institution in both informing and reading out brain stimulation effects with EEG and fMRI.

Your role: You will spearhead our efforts to develop precision brain stimulation protocols using MRI and EEG read-outs to inform transcranial magnetic stimulation, leveraging newly developed transcranial stimulation technology. You will design and conduct EEG-informed precision stimulation experiments, acquiring and analyzing data, and writing the data up for publication and dissemination.

Essential skills & experience:
• You have extensive experience with transcranial brain stimulation (preferentially transcranial magnetic stimulation)
• You have experience in conducting neurophysiology (EEG) or neuroimaging (MRI) experiments in humans.
• You have strong signal processing and analysis skills in the field of electrophysiology or brain mapping
• You hold a PhD degree in neuroscience, biomedical/electrical engineering, clinical medicine, or related field
• Prior refereed journal publications
• Strong written and interpersonal communication skills

Advantageous skills & experience:
• Prior experience with EEG or MRI applications in patients with brain disorders
• Prior experience with teaching and supervision of students and technicians

Working at DRCMR. You will become a member of the Brain Circuit Modulation & Therapy group, headed by Hartwig Siebner at the DRCMR (www.drcmr.dk) based at Copenhagen University Hospital Hvidovre. You will have the opportunity to collaborate with engineers, neurologists, psychologists, and interact with other groups at DRCMR.

DRCMR is a leading research center for biomedical MRI in Europe. Approximately 75 researchers from a diverse range of disciplines are currently pursuing basic and clinically applied research. The DRCMR is embedded in the Dept. for Radiology and Nuclear Medicine at the Copenhagen University Hospital Hvidovre, Copenhagen, Denmark. DRCMR has a state-of-the-art MR-research infrastructure enabling translational research, which includes a pre-clinical 7T MR scanner, six whole-body MR scanners (one 7T, four 3T and a 1.5T scanner) and a High-Performance Computer cluster. The DRCMR has pre-clinical labs, a neuropsychology laboratory, an EEG laboratory, and five laboratories for precision brain circuit stimulation. It is situated ~25mins cycle ride from central Copenhagen, a city consistently ranked one of the highest in the world for quality of life [link].

Recent Publications

Madsen MAJ, Povazan M, Wiggermann V, Lundell H, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2024. Association of cortical lesions with regional glutamate, GABA, N-Acetylaspartate, and Myoinositol levels in patients with multiple sclerosis. Neurology. Accepted

Stærkind H, Jensen K, Müller JH, Boer VO, Polzik ES, Petersen ET. 2024. High-field optical cesium magnetometer for magnetic resonance imaging. PRX Quantum. 5(2): 020320. https://doi.org/10.1103/PRXQuantum.5.020320

Stærkind H, Jensen K, Müller JH, Boer VO, Petersen ET, Polzik ES. 2023. Precision measurement of the excited state Landé g-factor and diamagnetic shift of the Cesium D2 line. Phys Rev X. 13(2): 021036. https://doi.org/10.1103/PhysRevX.13.021036

Boer VO, Pedersen JO, Arango N, Kuang I, Stockmann J, Petersen ET. 2022. Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field. MAGMA. 35(6): 943-951. https://doi.org/10.1007/s10334-022-01014-6

Andersen M, Laustsen M, Boer V. Accuracy investigations for volumetric head-motion navigators with and without EPI at 7 T. 2022. Magn Reson Med. 88(3): 1198-1211. https://doi.org/10.1002/mrm.29296

Madsen MAJ, Wiggermann V, Marques MFM, Lundell H, Cerri S, Puonti O, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2022. Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study. Brain. 145(10): 3522-3535. https://doi.org/10.1093/brain/awac203

Sandström KO, Baltzersen OB, Marsman A, Lemvigh CK, Boer VO, Bojesen KB, Nielsen MØ, Lundell H, Sulaiman DK, Sørensen ME, Fagerlund B, Lahti AC, Syeda WT, Pantelis C, Petersen ET, Glenthøj BY, Siebner HR, Ebdrup BH. 2022. Add-on memantine to dopamine antagonism to improve negative symptoms at first psychosis – the AMEND trial protocol. Front Psychiatry. 13: 889572. https://doi.org/10.3389/fpsyt.2022.889572

Madelung CF, Meder D, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Petersen ET, Hejl A-M, Løkkegaard A, Siebner HR. 2022. Locus coeruleus shows a spatial pattern of structural disintegration in Parkinson's disease. Movement Disord. 37(3): 479-489. https://doi.org/10.1002/mds.28945

Recent Conference Abstracts

Stemmerik M, Beha G, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Using high-field magnetic resonance spectroscopy to measure muscle glycogen in patients with McArdle disease. Neuromuscular Disorders. 32. S73-S74.

Beha G, Stemmerik M, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Quantification of glycogen distribution in late-onset Pompe patients using 7 Tesla C13 NMR spectroscopy. Neuromuscular Disorders. 32. S73.

Madsen MAJ, Wiggermann V, Povazan M, Lundell H, Boer VO, Marsman A, Blinkenberg MB, Romme Christensen J, Sellebjerg FT, Siebner HR. 2022. Linking cortical demyelination to changes in brain metabolism in multiple sclerosis: a 7T MR spectroscopy study. ECTRIMS annual (virtual) meeting.

Güler S, Costa G, Boer V, Paulides M, Baltus P, Petersen E, Zivkovic I. 2022. Shielded coaxial cable coils: the array configuration for maximized central SNR at 7T MRI. Joint Annual Meeting ISMRM-ESMRMB, 31^st annual ISMRM meeting.

Güler S, Zhurbenko V, Zivkovic I, Boer V, Petersen ET. 2022. Second resonance mode ensure intrinsic low coupling between elements on shielded-coaxial-cable coil designs. Joint Annual Meeting ISMRM-ESMRMB, 31^st annual ISMRM meeting.