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Danish National 7T MR Project

As of 2015, the DRCMR operates one of the strongest MR scanners worldwide and the only one of its caliber in Denmark. The purchase of ths state-of-the-art MR system from Phillips Healthcare was made possible by the John and Birthe Meyer Foundation and the Danish Agence for Science, Technology and Innovation.

The field strength of 7 tesla (T) corresponds with roughly 140.000 times the earth magnetic field and is generated by a 44 ton superconducting electromagnet with its inner part cooled 7T log finalby liquid helium to around -270°C/-450 °F/3 K. 

The ultra-high magnetic field strength of 7T enables us to uncover structure, function and chemistry of the body’s interior with unprecedented precision. As such, it gives us a much more detailed insight into human (patho)physiology as compared to clinical MR scanners, which typically range from 1.5 to 4T. Particularly brain research benefits from the ultra-high field strength.

In the scope of the Danish National 7T MR Project, the 7T scanner is available as a research resource to the whole of Denmark. 7T MR scanners are not approved for clinical use, hence the scanner is fully dedicated to research.

 

Current 7T projects include:

  • Brain diffusion-weighted imaging (DWI) and spectroscopy (DWS) in multiple sclerosis (MS)
  •  Brain proton magnetic resonance spectroscopy (1H-MRS) in schizophrenia
  •  Brain 1H-MRS, structural imaging and cognition across the lifespan
  •  Liver carbon (13C) MRS in diabetes
  •  A particular focus lies on the development of new MR methodologies and hardware.

 

National collaborations involve:

  • Technical University of Denmark
  • University of Copenhagen
  • Copenhagen University Hospitals

 

International collaborations have been established with:

  • Lund University, Sweden
  • Leiden University Medical Center, The Netherlands
  • University Medical Center Utrecht, The Netherlands
  • Korea Basic Science Institute, South Korea

 

 

 

 

Selected Publications

Mortensen KN, Lilius T, Rosenholm M, Sigurðsson B, Kelley DH, Nedergaard M. Perivascular cerebrospinal fluid inflow matches interstitial fluid efflux in anesthetized rats. iScience. 2025 May 16;28(5).

Ölmestig J, Mortensen KN, Thomas MB, Fagerlund B, Naveed N, Nordling MM, Nielsen MK, Rasmussen BS, Christensen H, Iversen HK, Poulsen MB. Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial. Stroke. 2025 Jul 28.

Ölmestig J, Mortensen KN, Fagerlund B, Naveed N, Nordling MM, Christensen H, Iversen HK, Poulsen MB, Siebner HR, Kruuse C. Cerebral blood flow and cognition after 3 months tadalafil treatment in small vessel disease (ETLAS-2): study protocol for a randomized controlled trial. Trials. 2024 Aug 29;25(1):570.

Group Members

Kristian Nygaard Mortensen

Henrik Lundell

Rasmus Hvass Hansen

Show all group members (7)

External Collaborators

Prof. Matthias van Osch
C.J. Gorter Center for high field MRI, Leiden University


Ass. Prof. Henrik W. Schytz
Danish Headache Center & University of Copenhagen


Prof. Christina Kruuse
Rigshospitalet & University of Copenhagen