Our overarching goal is to unravel the underlying mechanism in brain development, aging and diseases. We also advance our understanding of how therapeutic interventions act on the brain, for example in patients with multiple sclerosis, Parkinson's disease, traumatic brain injury, dementia, anorexia, schizophrenia, and depression.
Our overarching goal
Our overarching goal is to unravel the underlying mechanism in brain development, aging and diseases. We also advance our understanding of how therapeutic interventions act on the brain, for example in patients with multiple sclerosis, Parkinson's disease, traumatic brain injury, dementia, anorexia, schizophrenia, and depression.
Selected Publications
Mortensen KN, Lilius T, Rosenholm M, Sigurðsson B, Kelley DH, Nedergaard M. Perivascular cerebrospinal fluid inflow matches interstitial fluid efflux in anesthetized rats. iScience. 2025 May 16;28(5).
Ölmestig J, Mortensen KN, Thomas MB, Fagerlund B, Naveed N, Nordling MM, Nielsen MK, Rasmussen BS, Christensen H, Iversen HK, Poulsen MB. Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial. Stroke. 2025 Jul 28.
Ölmestig J, Mortensen KN, Fagerlund B, Naveed N, Nordling MM, Christensen H, Iversen HK, Poulsen MB, Siebner HR, Kruuse C. Cerebral blood flow and cognition after 3 months tadalafil treatment in small vessel disease (ETLAS-2): study protocol for a randomized controlled trial. Trials. 2024 Aug 29;25(1):570.
External Collaborators
Prof. Matthias van Osch
C.J. Gorter Center for high field MRI, Leiden University
Ass. Prof. Henrik W. Schytz
Danish Headache Center & University of Copenhagen
Prof. Christina Kruuse
Rigshospitalet & University of Copenhagen