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MRI acquisition and analysis course 2010

Course title: Magnetic Resonance Imaging Techniques and Analysis

Content and format: The course covers introductory MRI acquisition and image processing methods. Analysis of functional imaging data will be covered in detail. The first half of the course is mainly lectures on MR-basics. It also includes data acquisition for the remaining part of the course that is focused on hands-on data analysis.

The course starts at a level requiring little or no MR experience. A technical background is not required. The target audience is employees and students at the MR department but the course is open and free for external participants.

DRCMR employees, students, new-comers and co-workers are given priority if we (against expectations) have to limit the number of participants due to space limitations.

The course covers the basics  needed to follow the somewhat more technical course Medical Magnetic Resonance Imaging offered as part of the Medicine&Technology program at the Technical University of Denmark in the spring, and which is also available for non-DTU-students under "Open University".

Dates and time: Starting September 21st 2010, the course is given Tuesdays 14:00-16:00 in the conference room of the MR-department at Hvidovre Hospital (dept. 340).

Registration: Please register below.

Literature and software: Course notes and relevant articles are provided during the course. Before the first lecture, it is recommended to install the software freely available at http://www.drcmr.dk/bloch as this will play an important role in the acquisition part of the course (access to the software is not needed during lectures). The same applies to the SPM software available at http://www.fil.ion.ucl.ac.uk/spm/ which will be used during the analysis part. The latter software package requires a working installation of Matlab as described on the SPM home page.

Credit: The course has a workload corresponding to 2-5 ECTS points depending on exams/assignments taken (2 is 1/15 semester workload) but you do not automatically get credit for the course in any educational institution. You may apply for credit at your school, but be aware that no general evaluation is planned, which may be required for a credit bearing course. This can possibly be arranged on an individual basis upon request, and is required for the organizers to recommend more than 2 ECTS.

Language: The course is given in English, or in Danish if all participants are Danish speaking.

Lecturers: The acquisition part is coordinated by Lars G. Hanson , and the analysis part by Arnold Skimminge. Lectures are by the organizers, Lise Vejby Søgaard and Kristoffer H. Madsen.

Preliminary program:

September 21th, MRI acquisition, part 1:

  • Sections "Magnetic Resonance" until "Sequences" in MR notes are discussed during the coming few weeks (the English and Danish versions are similar).
  • Protons, spin, net magnetization, precession, radio waves, resonance, relaxation, rotating and stationary frames of reference, T1 and T2.



September 28th, MRI acquisition, part 2:

  • Relaxation time weighting. Dephasing, refocusing, T2*, spin echoes, and sequences.

 

October 5th, MRI acquisition, part 3:

  • Earlier subjects continued. Contrast overview, slice selection spectroscopy.

 

October 12th: Spectroscopy continued, dephasing/refocusing, flow/diffusion measurements.

October 19th: No lecture.

 

October 26th, MRI acquisition, part 4:

  • Saturation and inversion.
  • MR notes from "Imaging" and beyond are covered during the coming weeks.
  • Gradients, image-formation and k-space. Echo time revisited.

 

November 2nd, MRI acquisition, part 5:

  • Imaging continued, field strength issues, coils and safety.

 

November 9th:  MRI acquisition, part 6:

  • Sequence elements, k-space trajectories, artifacts (distortions, ghosting and aliasing), noise and image quality quantification.

 

November 16th, MRI analysis, preprocessing

  • Introduction to analysis section of the course.
  • Introduction to SPM8.
  • fMRI preprocessing.
  • N-back hands-on preprocessing.

 

November 23rd, MRI analysis, first level analysis:

  • Introduction to fMRI statistics.
  • First level analysis.
  • N-back hands-on first level specification and estimation.

 

November 30th: MRI analysis, contrasts:

  • Introduction to statistical inference.
  • Contrasts, plotting and visualizations.
  • N-back hands-on statistical inference.

 

December 7th: MRI analysis, part 4:

  • Scripting and batching basics
  • N-back hands-on scripting

 

December 14th: MRI analysis, second level

  • Second level analysis
  • N-back hands-on group study

 

December 21st: MRI analysis, second level inference

  • Contrasts, plotting and visualizations.
  • N-back hands-on second level inference.

 

Course title: Magnetic Resonance Imaging Techniques and Analysis

Content and format: The course covers introductory MRI acquisition and image processing methods. Analysis of functional imaging data will be covered in detail. The first half of the course is mainly lectures on MR-basics. It also includes data acquisition for the remaining part of the course that is focused on hands-on data analysis.

The course starts at a level requiring little or no MR experience. A technical background is not required. The target audience is employees and students at the MR department but the course is open and free for external participants.

DRCMR employees, students, new-comers and co-workers are given priority if we (against expectations) have to limit the number of participants due to space limitations.

The course covers the basics  needed to follow the somewhat more technical course Medical Magnetic Resonance Imaging offered as part of the Medicine&Technology program at the Technical University of Denmark in the spring, and which is also available for non-DTU-students under "Open University".

Dates and time: Starting September 21st 2010, the course is given Tuesdays 14:00-16:00 in the conference room of the MR-department at Hvidovre Hospital (dept. 340).

Registration: Please register below.

Literature and software: Course notes and relevant articles are provided during the course. Before the first lecture, it is recommended to install the software freely available at http://www.drcmr.dk/bloch as this will play an important role in the acquisition part of the course (access to the software is not needed during lectures). The same applies to the SPM software available at http://www.fil.ion.ucl.ac.uk/spm/ which will be used during the analysis part. The latter software package requires a working installation of Matlab as described on the SPM home page.

Credit: The course has a workload corresponding to 2-5 ECTS points depending on exams/assignments taken (2 is 1/15 semester workload) but you do not automatically get credit for the course in any educational institution. You may apply for credit at your school, but be aware that no general evaluation is planned, which may be required for a credit bearing course. This can possibly be arranged on an individual basis upon request, and is required for the organizers to recommend more than 2 ECTS.

Language: The course is given in English, or in Danish if all participants are Danish speaking.

Lecturers: The acquisition part is coordinated by Lars G. Hanson , and the analysis part by Arnold Skimminge. Lectures are by the organizers, Lise Vejby Søgaard and Kristoffer H. Madsen.

Preliminary program:

September 21th, MRI acquisition, part 1:

  • Sections "Magnetic Resonance" until "Sequences" in MR notes are discussed during the coming few weeks (the English and Danish versions are similar).
  • Protons, spin, net magnetization, precession, radio waves, resonance, relaxation, rotating and stationary frames of reference, T1 and T2.



September 28th, MRI acquisition, part 2:

  • Relaxation time weighting. Dephasing, refocusing, T2*, spin echoes, and sequences.

 

October 5th, MRI acquisition, part 3:

  • Earlier subjects continued. Contrast overview, slice selection spectroscopy.

 

October 12th: Spectroscopy continued, dephasing/refocusing, flow/diffusion measurements.

October 19th: No lecture.

 

October 26th, MRI acquisition, part 4:

  • Saturation and inversion.
  • MR notes from "Imaging" and beyond are covered during the coming weeks.
  • Gradients, image-formation and k-space. Echo time revisited.

 

November 2nd, MRI acquisition, part 5:

  • Imaging continued, field strength issues, coils and safety.

 

November 9th:  MRI acquisition, part 6:

  • Sequence elements, k-space trajectories, artifacts (distortions, ghosting and aliasing), noise and image quality quantification.

 

November 16th, MRI analysis, preprocessing

  • Introduction to analysis section of the course.
  • Introduction to SPM8.
  • fMRI preprocessing.
  • N-back hands-on preprocessing.

 

November 23rd, MRI analysis, first level analysis:

  • Introduction to fMRI statistics.
  • First level analysis.
  • N-back hands-on first level specification and estimation.

 

November 30th: MRI analysis, contrasts:

  • Introduction to statistical inference.
  • Contrasts, plotting and visualizations.
  • N-back hands-on statistical inference.

 

December 7th: MRI analysis, part 4:

  • Scripting and batching basics
  • N-back hands-on scripting

 

December 14th: MRI analysis, second level

  • Second level analysis
  • N-back hands-on group study

 

December 21st: MRI analysis, second level inference

  • Contrasts, plotting and visualizations.
  • N-back hands-on second level inference.

 

Selected Publications

2021

Albers KJ, Ambrosen KS, Liptrot MG, Dyrby TB, Schmidt MN, Mørup M. 2021. Using connectomics for predictive assessment of brain parcellations. NeuroImage. 238:1-18. https://doi.org/10.1016/j.neuroimage.2021.118170

He Y, Aznar S, Siebner HR, Dyrby TB. 2021. In vivo tensor-valued diffusion MRI of focal demyelination in white and deep grey matter of rodents. NeuroImage. Clinical. 30:1-9. https://doi.org/10.1016/j.nicl.2021.102675

Lundell H, Ingo C, Dyrby TB, Ronen I. 2021. Cytosolic diffusivity and microscopic anisotropy of N-acetyl aspartate in human white matter with diffusion-weighted MRS at 7 T. NMR in Biomedicine. 34(5):1-14. https://doi.org/10.1002/nbm.4304

Perens J, Salinas CG, Skytte JL, Roostalu U, Dahl AB, Dyrby TB, Wichern F, Barkholt P, Vrang N, Jelsing J, Hecksher-Sørensen J. 2021. An Optimized Mouse Brain Atlas for Automated Mapping and Quantification of Neuronal Activity Using iDISCO+ and Light Sheet Fluorescence Microscopy. Neuroinformatics. 19(3):433-446. https://doi.org/10.1007/s12021-020-09490-8

Skoven C, Tomasevic L, Kvitsiani D, Dyrby TB, Siebner HR. 2021. Profiling the transcallosal response of rat motor cortex evoked by contralateral optogenetic stimulation of glutamatergic cortical neurons. bioRxiv. 1-31. https://doi.org/10.1101/2021.04.15.439619

2020

Ambrosen, K. S., Eskildsen, S. F., Hinne, M., Krug, K., Lundell, H., Schmidt, M. N., van Gerven, M. A. J., Mørup, M. & Dyrby, T. B. (2020). Validation of structural brain connectivity networks: The impact of scanning parameters. NeuroImage. 204, p. 1-13, 116207.

Andreasen, S. H., Andersen, K. W., Conde, V., Dyrby, T. B., Puonti, O. T., Kammersgaard, L. P., Madsen, C. G., Madsen, K. H., Poulsen, I. & Siebner, H. R. (2020). Limited Colocalization of microbleeds and microstructural changes after severe traumatic brain injury. Journal of Neurotrauma. 37, 4, p. 581-592.

Cavaliere, C., Aiello, M., Soddu, A., Laureys, S., Reislev, N. L., Ptito, M. & Kupers, R. (2020).
Organization of the commissural fiber system in congenital and late-onset blindness.
NeuroImage. Clinical. 25, 102133.  

Nath, V., Schilling, K. G., Parvathaneni, P., Huo, Y., Blaber, J. A., Hainline, A. E., Barakovic, M., Rafael-Patino, J., Frigo, M., Girard, G., Thiran, J-P., Daducci, A., Rowe, M., Rodrigues, P., Prčkovska, V., Aydogan, D. B., Sun, W., Shi, Y., Parker, W. A., Ould Ismail, A. A., Verma, R., Cabeen, R. P., Toga, A. W., Newton, A. T., Wasserthal, J., Neher, P., Maier-Hein, K., Savini, G., Palesi, F., Kaden, E., Wu, Y., He, J., Feng, Y., Paquette, M., Rheault, F., Sidhu, J., Lebel, C., Leemans, A., Descoteaux, M., Dyrby, T. B., Kang, H. & Landman, B. A. (2020). Tractography reproducibility challenge with empirical data (TraCED): The 2017 ISMRM diffusion study group challenge. Journal of magnetic resonance imaging: JMRI. 51, 1, p. 234-249.

Barrett, R. L. C., Dawson, M., Dyrby, T. B., Krug, K., Ptito, M., D'Arceuil, H., Croxson, P. L., Johnson, P., Howells, H., Forkel, S. J., Dell'Acqua, F. & Catani, M. (2020). Differences in frontal network anatomy across primate species. The Journal of Neuroscience. 25 p., 1650-18.

Benavides, F. D., Jin Jo, H., Lundell, H., Edgerton, V. R., Gerasimenko, Y. & Perez, M. A. (2020).
Cortical and Subcortical Effects of Transcutaneous Spinal Cord Stimulation in Humans with Tetraplegia. The Journal of Neuroscience.

Postans, M., Parker, G. D., Lundell, H., Ptito, M., Hamandi, K., Gray, W. P., Aggleton, J. P., Dyrby, T. B., Jones, D. K. & Winter, M. (2020). Uncovering a Role for the Dorsal Hippocampal Commissure in Recognition Memory. Cerebral Cortex. 15 p., bhz143.

Romascano, D., Barakovic, M., Rafael-Patino, J., Dyrby, T. B., Thiran, J-P. & Daducci, A. (2020).
ActiveAxADD: Toward non-parametric and orientationally invariant axon diameter distribution mapping using PGSE. Magnetic Resonance in Medicine.

2019

Bauer, C. (2019). Structural correlates of fatigue in multiple sclerosis assessed with magnetic resonance imaging (MRI). Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Alexander, D. C., Dyrby, T. B., Nilsson, M. & Zhang, H. (2019). Imaging brain microstructure with diffusion MRI: practicality and applications. N M R in Biomedicine. 32, 4, p. 1-26, e3841.

Borg, L., Sporring, J., Dam, E. B., Dahl, V. A., Dyrby, T. B., Feidenhans'l, R., Dahl, A. B. & Pingel, J. (2019). Muscle fibre morphology and microarchitecture in cerebral palsy patients obtained by 3D synchrotron X-ray computed tomography. Computers in Biology and Medicine. 107, p. 265-269.

Innocenti, G. M., Caminiti, R., Rouiller, E. M., Knott, G., Dyrby, T. B., Descoteaux, M. & Thiran, J-P. (2019). Diversity of Cortico-descending Projections: Histological and Diffusion MRI Characterization in the Monkey. Cerebral Cortex. 29, 2, p. 788-801.

Innocenti, G. M., Dyrby, T. B., Girard, G., St-Onge, E., Thiran, J-P., Daducci, A. & Descoteaux, M. (2019). Topological principles and developmental algorithms might refine diffusion tractography. Brain structure & function. 224, 1, p. 1-8.

Lundell, H., Nilsson, M., Dyrby, T. B., Parker, G. J. M., Cristinacce, P. L. H., Zhou, F-L., Topgaard, D. & Lasič, S. (2019). Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail. Scientific Reports. 9, 1, p. 1-12, 9026.

Sangari, S., Lundell, H., Kirshblum, S. & Perez, M. A. (2019). Residual Descending Motor Pathways Influence Spasticity after Spinal Cord Injury. Annals of Neurology. 86, 1, p. 28-41.

Schilling, K. G., Nath, V., Hansen, C., Parvathaneni, P., Blaber, J., Gao, Y., Neher, P., Aydogan, D. B., Shi, Y., Ocampo-Pineda, M., Schiavi, S., Daducci, A., Girard, G., Barakovic, M., Rafael-Patino, J., Romascano, D., Rensonnet, G., Pizzolato, M., Bates, A., Fischi, E., Thiran, J-P., Canales-Rodríguez, E. J., Huang, C., Zhu, H., Zhong, L., Cabeen, R., Toga, A. W., Rheault, F., Theaud, G., Houde, J-C., Sidhu, J., Chamberland, M., Westin, C-F., Dyrby, T. B., Verma, R., Rathi, Y., Irfanoglu, M. O., Thomas, C., Pierpaoli, C., Descoteaux, M., Anderson, A. W. & Landman, B. A. (2019). Limits to anatomical accuracy of diffusion tractography using modern approaches.
NeuroImage. 185, p. 1-11.

Lasič, S., Topgaard, D., Nilsson, M. & Lundell, H. (2019). A method of performing diffusion weighted magnetic resonance measurements on a sample. IPC nr. G01R33/56341, G01R33/4835, G01R33/543, G01R33/5608, A61B5/055, Patentnr. 16348580, 9 nov. 2017, Prioritetsdato 9 nov. 2016, Prioritetsnr. SE1651469-7 2019.

Lindhøj, M. B., Henriksen, T., Pedersen, L. & Sporring, J. (2019). Using a high-level parallel programming language for GPU-accelerated tomographic reconstruction. (Accepteret/In press) Using a high-level parallel programming language for GPU-accelerated tomographic reconstruction. p. 27-32.

2018

Lasič, S., Lundell, H., Topgaard, D. & Dyrby, T. B. (2018). Effects of imaging gradients in sequences with varying longitudinal storage time-Case of diffusion exchange imaging. Magnetic Resonance in Medicine. 79, p. 2228-2235.

Nielsen, J. S., Dyrby, T. B. & Lundell, H. (2018). Magnetic resonance temporal diffusion tensor spectroscopy of disordered anisotropic tissue. Scientific Reports. 8, 2930.

Sickmann, H. M., Skoven, C., Bastlund, J. F., Dyrby, T. B., Plath, N., Kohlmeier, K. A. & Kristensen, M. P. (2018). Sleep patterning changes in a prenatal stress model of depression.
Journal of Developmental Origins of Health and Disease. 9, 1, p. 102-111.

Alexander, D. C., Dyrby, T. B., Nilsson, M. & Zhang, H. (2018). Imaging brain microstructure with diffusion MRI: practicality and applications. N M R in Biomedicine.

Dogonowski, A. M., Andersen, K. W., Sellebjerg, F., Schreiber, K., Madsen, K. H. & Siebner, H. R. (2018). Functional neuroimaging of recovery from motor conversion disorder: A case report. NeuroImage.

Dyrby, T. B., Innocenti, G., Bech, M. & Lundell, H. (2018). Validation strategies for the interpretation of microstructure imaging using diffusion MRI. NeuroImage.

Innocenti, G. M., Caminiti, R., Rouiller, E. M., Knott, G., Dyrby, T. B., Descoteaux, M. & Thiran, J-P. (2018). Diversity of Cortico-descending Projections: Histological and Diffusion MRI Characterization in the Monkey. Cerebral Cortex.

2017

Røge, R., Sandø Ambrosen, K. M., Albers, K. J., Eriksen, C. T., Liptrot, M. G., Schmidt, M. N., Madsen, K. H. & Mørup, M. (2017). Whole Brain Functional Connectivity Predicted by Indirect Structural Connections.

Lundell, H. M. H., Ingo, C., Dyrby, T. B. & Ronen, I. (2017). Accurate estimation of intra-axonal diffusivity and anisotropy of NAA in humans at 7T.

Lundell, H. M. H., Nilsson, M., Dyrby, T. B., Parker, G. J. M., Cristinacce, P. L. H., Zhou, F., Topgaard, D. & Lasic, S. (2017). Microscopic anisotropy with spectrally modulated q-space trajectory encoding.

2016

Large I, Bridge H, Ahmed B, Clare S, Kolasinski J, Lam WW, Miller KL, Dyrby TB, Parker AJ, Smith JET, Daubney G, Sallet J Bell AH, Krug K, (2016). Individual differences in the alignment of structural and functional markers of the V5/MT complex in primates, Cerebral Cortex, Accepted.

Donahue C, Sotiropoulos S, Jbabdi S, Hernandez-Fernandez M, Beherens T, Dyrby TB, Kennedy H, Knoblauch K, Coalson T, Glasser M, Van Essen D, (2016). Using Diffusion Tractography to Predict Cortical Connection Strength and Distance: A Quantitative Comparison with Tracers in the Monkey, Journal Neuroscience, 36(25): 6758-6770

Innocenti GM, Dyrby TB, Winther Andersen K, Rouillier EM, Caminiti R (2016). The crossed projection to the striatum in two species of monkey and in humans: Behavioral and evolutionary significance, Cerebral Cortex,  doi: 10.1093/cercor/bhw161

2015

Reislev NL, Dyrby TB, Siebner HR, Kupers R, (2015). Simultaneous assessment of white matter changes in microstructure and connectedness in the blind brain, Neural Plasticity, Article ID 795865.

Ratzer R, Iversen P, Börnsen L, Dyrby TB, Christensen JR, Ammitzbøll C, Madsen CG, Garde E, Andersen B, Hyldstrup L, Sørensen PS, Siebner HR, Sellebjerg F, (2015). Monthly oral methylprednisolone pulse treatment in progressive multiple sclerosis, Multiple Sclerosis Journal (accepted).

Shemesh N, Jespersen SN, Alexander DC, Cohen Y, Drobnjak I, Dyrby TB, Finsterbusch J, Koch MA, Kuder T, Laun F, Lawrenz M, Lundell H, Mitra PP, Nilsson M, Özarslan E, Topgaard D, Westin CF, Conventions and nomenclature for double diffusion encoding NMR and MRI, Magn Reson Med, 2015 (accepted)

Barthélemy D, Willerslev-Olsen M, Lundell H, Biering-Sørensen F, Nielsen JB. (2015). Assessment of transmission in specific descending pathways in relation to gait and balance following spinal cord injury, Prog Brain Res. 218:79-101.

Knösche TR, Anwander A, Liptrot MG, Dyrby TB, (2015). Validation of Tractography – Comparison with Manganese Tracing, Human Brain Mapping, Human Brain Mapping, DOI: 10.1002/hbm.22902.

Reislev NL, Kupers R, Siebner HR, Ptito M, Dyrby TB, (2015). Blindness alters the microstructure of the ventral but not the dorsal visual stream. Brain Structure and Function, DOI: 10.1007/s00429-015-1078-8.

Sickmann HM, Arentzen TS, Dyrby TB, PlathN, Kristensen MP, (2015). Prenatal Stress Produces Sex Specific Changes in Depression-like Behavior in Rats: Implications for increased vulnerability in females, Journal of Developmental Origins of Health and Disease, (Accepted).

Lundell H, Sønderby CK, Dyrby TB, (2015). Diffusion weighted imaging with circularly polarized oscillating gradients,Magn Reson Med., 73(3), 171:1176.

Daducci A, Canales-Rodriguez EJ, Zhang H, Dyrby TB, Alexander DC, Thiran JP, (2015). Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data, Neuroimage, 35, 32-44.

2014

Dyrby TB, Lundell H, Burke MW, Reislev NL, Paulson OB, Ptito M, Siebner HR, (2014). Interpolation of diffusion weighted imaging datasets, NeuroImage, 103, 202–213.

Jespersen SN, Lundel H, Sønderby C, Dyrby TB, (2014). Commentary on ”Microanisotropy imaging: quantification of microscopic diffusion anisotropy and orientation of order parameter by diffusion MRI with magic-angle spinning of the q-vector”, Frontiers in Physics, doi: 10.3389/fphy.2014.00028.

Lundell HM, Alexander DC, Dyrby TB, (2014). High angular resolution diffusion imaging with stimulated echoes: compensation and correction in experiment design and analysis, NMR in Biomedicine.

Liptrot GM, Sidaros K, Dyrby TB, (2014). Addressing The Path-Length-Dependency Confound In White Matter Tract Segmentation, PLOS ONE, 9 (5), e96247.

Lyksborg M, Siebner HR, Sørensen PS, Blinkenberg M, Parker GJM, Dogonowski A, Garde E, Larsen R, Dyrby TB, (2014). Secondary progressive and relapsing remitting multiple sclerosis leads to motor-related decreased anatomical connectivity,  PLOS ONE 9 (4), e95540.

Lundell HM, Sønderby CK, Dyrby TB, (2014). Diffusion weighted imaging with circularly polarized oscillating gradients,Magn Reson Med. (accepted).

Christensen JR, Ratzer R, Börnsen L, Lyksborg M, Garde E, Dyrby TB, Siebner HR, Sørensen PS, Sellebjerg F, (2014). Natalizumab in progressive MS – results of an open-label phase 2A proof-of- concept trial. Neurology (accepted). 

Sønderby, C. K., Lundell, H. M., Søgaard, L. V. and Dyrby, T. B. (2014). Apparent exchange rate imaging in anisotropic systems. Magn Reson Med., 72(3), 756-762.

2013

Jespersen SN, Lundell H, Sønderby KS, Dyrby TB, (2013). Rotationally invariant sampling of double pulsed field gradient diffusion: estimating apparent compartment eccentricity, NMR in biomedicine, (in press).

Assaf Y, Alexander DC, Jones DK, Bizzi A, Behrens T, Clark C, Cohen Y, Dyrby TB, Huppi P, Knoesche T, LeBihan D, Parker GJM, (2013). CONNECT Consortium, The CONNECT project: Combining Macro- and Micro-structure, NeuroImage, 80, 273-282.

Dyrby TB, Søgaard LV, Hall MG, Ptito M, Alexander DC, (2013). Contrast and stability of the axon diameter index from microstructure imaging with diffusion MRI, Magnetic Resonance in Medicine. 70(3), 711:721.

2012

Lundell H, Barthelemy D, Biering-Sørensen F, Cohen-Adad J, Nielsen JB, Dyrby TB. (2012). Fast diffusion tensor imaging and tractography of the whole cervical spinal cord using point spread function corrected echo planar imaging., Magn Reson Med. 2012 Mar 6. doi: 10.1002/mrm.24235. [Epub ahead of print].

2011

Zhang H, Dyrby TB, Alexander DC., (2011) Axon diameter mapping in crossing fibers with diffusion MRI, Med Image Comput Comput Assist Interv.;14(Pt 2):82-9.

Lundell H, Nielsen J  B, Ptito M, Dyrby T B. (2011). Distribution of collateral fibers in the monkey cervical spinal cord detected with diffusion weighted magnetic resonance imaging. NeuroImage, 56(3):923-9.

Dyrby TB, Baaré WFC, Alexander DC, Jelsing J, Garde E, Søgaard LV, (2011). An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion weighted imaging datasets. Hum Brain Mapp. 2011 Apr;32(4):544-63.

2010

Alexander DC, Hubbard PL, Hall MG, Moore EA, Ptito M, Parker GJ, Dyrby TB. Orientationally invariant indices of axon diameter and density from diffusion MRI. Neuroimage. 2010, 52(4):1374-89.

2009

Stavngaard T, Søgaard LV, Batz M, Schreiber LM, Dirksen A. Progression of emphysema evaluated by MRI using hyperpolarized 3He (HP 3He) measurements in patients with alpha-1 antitrypsin deficiency (A1AT), compared with CT and lung function tests. Acta Radiol. 2009, 50(9):1019-26.

2008

Sidaros A, Engberg AW, Sidaros K, Liptrot MG, Herning M, Petersen P, Paulson OB, Jernigan TL, Rostrup E. Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: a longitudinal study. Brain 2008, 131(Pt 2), 559-572.

2007

Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, Hay-Schmidt A, Eriksen N, Pakkenberg B, Paulson OB, Jelsing J. Validation of in vitro probabilistic tractography. Neuroimage 2007, 37(4), 1267

Group Members

Tim Dyrby

Group Leader

Samo Lasic

Mariam Andersson

Show all group members (10)

External Collaborators

Associate Prof. Sune Jespersen

CFIN, AArhus University, Denmark


Prof. Jean-Philippe Thiran

EPFL, Lausanne, Switzerland


Associate Prof. Itamar Ronen

Leiden University Medical Center, Leiden, The Netherlands


Prof. Giorgio Innocenti

Karolinska Institut, Stockhom, Sweden


Prof. Daniel C. Alexander

University London College (UCL), London, United Kingdom


Dr. Ivana Drobnajk

UCL, United Kingdom


Prof. Geoff JM Parker

Manchester University, Manchester, United Kingdom


Prof. Bente Pakkenberg

Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark


Associate Prof. Morten Mørup

Technical University of Deamark (DTU), Lyngby, Denmark