[EXPIRED] The Capital Region of Copenhagen is looking for a Research Fellow in Advanced 3T & 7T MRI and MRS for Neuroscience Applications

If you are a team-oriented MR researcher eager to unleash the full potentials of high- and ultra-high field MRI and MRS through novel software and hardware solutions, then you might be the person we are looking for!

A 4-year Research Fellow position in advanced 3T & 7T MRI/MRS applications.

As a researcher at the Danish Research Centre for Magnetic Resonance (DRCMR) you will support new and ongoing studies on a few research scanners and have the freedom to develop novel MRI/MRS sequences, hardware and processing methods primarily targeting neuroscientific applications. We have a Philips 7T research only scanner with 2- and 8-channel transmit, 32 receive and 64 shim channels in addition to the standard 3rd order shim.

You will be working closely with a multidisciplinary team of engineers, physicists, biomedical and clinical experts, who are developing and applying exciting and cutting-edge microstructural, X-nuclei imaging and spectroscopy techniques primarily for 7T, but also 3T studies. You will be part of the Ultra-high field MR group (www.drcmr.dk/7t).

DRCMR is one of the leading research centers for biomedical MRI in Europe (www.drcmr.dk). Our interdisciplinary research is geared to triangulate between MR physics, basic physiology, and clinical research. Approximately 70 researchers from a diverse range of disciplines work together to pursue basic and clinically applied MR research with a focus on structural, functional, and metabolic MRI of the human brain and its disorders. Collaboration is key at DRCMR – we do not expect any researcher to be able to do everything alone, but we expect everyone to be interested in sharing knowledge with colleagues.

The DRCMR is embedded in the Department of Radiology and Nuclear Medicine, a large diagnostic imaging department including all biomedical imaging modalities at Copenhagen University Hospital Hvidovre. DRCMR has close interaction with clinicians and radiologists and a state-of-the-art MR-research infrastructure, which includes a pre-clinical 7T MR scanner, six whole-body MR scanners (one 7T, four 3T and one 1.5T scanners), a hardware workshop and laboratory, a neuropsychology laboratory, an EEG laboratory, and two laboratories for non-invasive brain stimulation. The 7T is a national research infrastructure, serving internal and external users across Denmark.

Your profile:

You are a team-oriented, creative and enthusiastic researcher with:

A PhD degree in engineering, physics, biomedical sciences or a related field.
At least 2-3 years of doctoral and/or postdoctoral experience within advanced high or ultra-high field MRI (preferably on Philips systems).
A clear interest in MRI/MRS acquisition, reconstruction, and image analysis.
Excellent knowledge of MR physics and programming skills in C/C++, MATLAB or Python.
Ideally experience in MR sequence programming (preferably on Philips MR systems).
Affinity with medical applications.
Strong communication and collaborative skills.

Your tasks:

To work directly with other scientists to ensure that our research studies take full advantage of the 3T & 7T MR scanners by maximizing the clinical information available in the multi-parametric MRI images (structural, functional and other quantitative read-outs) and MRS including deuterium spectroscopy.
To support the 7T scanners daily operation, including MRI safety trainings.
To develop novel sequences and data analysis methods and bring these to applications in new projects.
To advance the field through your own research.
To engage in internal education, grant writing, knowledge dissemination, and publication of results in international, recognized scientific journals.

Your position:

You will be employed for a four-year period at the DRCMR and join the ultra-high field MR group.

Salary and Terms of Employment:

Salary, pension and terms of employment are in accordance with the agreement between the Danish Regions (Danske Regioner) and the relevant professional organization. The salary depends on background education and seniority. Further supplements can be negotiated. Note that candidates coming from abroad may be eligible for tax reductions. The position is open for candidates of all nationalities. We see diversity as strength and encourage everyone regardless of gender, age, ethnicity, disabilities or religion to apply.

Recent Publications

Madsen MAJ, Povazan M, Wiggermann V, Lundell H, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2024. Association of cortical lesions with regional glutamate, GABA, N-Acetylaspartate, and Myoinositol levels in patients with multiple sclerosis. Neurology. Accepted

Stærkind H, Jensen K, Müller JH, Boer VO, Polzik ES, Petersen ET. 2024. High-field optical cesium magnetometer for magnetic resonance imaging. PRX Quantum. 5(2): 020320. https://doi.org/10.1103/PRXQuantum.5.020320

Stærkind H, Jensen K, Müller JH, Boer VO, Petersen ET, Polzik ES. 2023. Precision measurement of the excited state Landé g-factor and diamagnetic shift of the Cesium D2 line. Phys Rev X. 13(2): 021036. https://doi.org/10.1103/PhysRevX.13.021036

Boer VO, Pedersen JO, Arango N, Kuang I, Stockmann J, Petersen ET. 2022. Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field. MAGMA. 35(6): 943-951. https://doi.org/10.1007/s10334-022-01014-6

Andersen M, Laustsen M, Boer V. Accuracy investigations for volumetric head-motion navigators with and without EPI at 7 T. 2022. Magn Reson Med. 88(3): 1198-1211. https://doi.org/10.1002/mrm.29296

Madsen MAJ, Wiggermann V, Marques MFM, Lundell H, Cerri S, Puonti O, Blinkenberg M, Romme Christensen J, Sellebjerg F, Siebner HR. 2022. Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study. Brain. 145(10): 3522-3535. https://doi.org/10.1093/brain/awac203

Sandström KO, Baltzersen OB, Marsman A, Lemvigh CK, Boer VO, Bojesen KB, Nielsen MØ, Lundell H, Sulaiman DK, Sørensen ME, Fagerlund B, Lahti AC, Syeda WT, Pantelis C, Petersen ET, Glenthøj BY, Siebner HR, Ebdrup BH. 2022. Add-on memantine to dopamine antagonism to improve negative symptoms at first psychosis – the AMEND trial protocol. Front Psychiatry. 13: 889572. https://doi.org/10.3389/fpsyt.2022.889572

Madelung CF, Meder D, Fuglsang SA, Marques MM, Boer VO, Madsen KH, Petersen ET, Hejl A-M, Løkkegaard A, Siebner HR. 2022. Locus coeruleus shows a spatial pattern of structural disintegration in Parkinson's disease. Movement Disord. 37(3): 479-489. https://doi.org/10.1002/mds.28945

Recent Conference Abstracts

Stemmerik M, Beha G, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Using high-field magnetic resonance spectroscopy to measure muscle glycogen in patients with McArdle disease. Neuromuscular Disorders. 32. S73-S74.

Beha G, Stemmerik M, Boer V, Marsman A, Jacobsen L, Petersen E, Vissing J. 2022. Quantification of glycogen distribution in late-onset Pompe patients using 7 Tesla C13 NMR spectroscopy. Neuromuscular Disorders. 32. S73.

Madsen MAJ, Wiggermann V, Povazan M, Lundell H, Boer VO, Marsman A, Blinkenberg MB, Romme Christensen J, Sellebjerg FT, Siebner HR. 2022. Linking cortical demyelination to changes in brain metabolism in multiple sclerosis: a 7T MR spectroscopy study. ECTRIMS annual (virtual) meeting.

Güler S, Costa G, Boer V, Paulides M, Baltus P, Petersen E, Zivkovic I. 2022. Shielded coaxial cable coils: the array configuration for maximized central SNR at 7T MRI. Joint Annual Meeting ISMRM-ESMRMB, 31^st annual ISMRM meeting.

Güler S, Zhurbenko V, Zivkovic I, Boer V, Petersen ET. 2022. Second resonance mode ensure intrinsic low coupling between elements on shielded-coaxial-cable coil designs. Joint Annual Meeting ISMRM-ESMRMB, 31^st annual ISMRM meeting.