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[EXPIRED] The Capital Region of Copenhagen is looking for a Research Fellow in Advanced 3T & 7T MRI and MRS for Neuroscience Applications


If you are a team-oriented MR researcher eager to unleash the full potentials of high- and ultra-high field MRI and MRS through novel software and hardware solutions, then you might be the person we are looking for!

A 4-year Research Fellow position in advanced 3T & 7T MRI/MRS applications.

As a researcher at the Danish Research Centre for Magnetic Resonance (DRCMR) you will support new and ongoing studies on a few research scanners and have the freedom to develop novel MRI/MRS sequences, hardware and processing methods primarily targeting neuroscientific applications. We have a Philips 7T research only scanner with 2- and 8-channel transmit, 32 receive and 64 shim channels in addition to the standard 3rd order shim.

You will be working closely with a multidisciplinary team of engineers, physicists, biomedical and clinical experts, who are developing and applying exciting and cutting-edge microstructural, X-nuclei imaging and spectroscopy techniques primarily for 7T, but also 3T studies. You will be part of the Ultra-high field MR group (www.drcmr.dk/7t).

DRCMR is one of the leading research centers for biomedical MRI in Europe (www.drcmr.dk). Our interdisciplinary research is geared to triangulate between MR physics, basic physiology, and clinical research. Approximately 70 researchers from a diverse range of disciplines work together to pursue basic and clinically applied MR research with a focus on structural, functional, and metabolic MRI of the human brain and its disorders. Collaboration is key at DRCMR – we do not expect any researcher to be able to do everything alone, but we expect everyone to be interested in sharing knowledge with colleagues.

The DRCMR is embedded in the Department of Radiology and Nuclear Medicine, a large diagnostic imaging department including all biomedical imaging modalities at Copenhagen University Hospital Hvidovre. DRCMR has close interaction with clinicians and radiologists and a state-of-the-art MR-research infrastructure, which includes a pre-clinical 7T MR scanner, six whole-body MR scanners (one 7T, four 3T and one 1.5T scanners), a hardware workshop and laboratory, a neuropsychology laboratory, an EEG laboratory, and two laboratories for non-invasive brain stimulation.  The 7T is a national research infrastructure, serving internal and external users across Denmark.

Your profile:

You are a team-oriented, creative and enthusiastic researcher with:

  • A PhD degree in engineering, physics, biomedical sciences or a related field.
  • At least 2-3 years of doctoral and/or postdoctoral experience within advanced high or ultra-high field MRI (preferably on Philips systems).
  • A clear interest in MRI/MRS acquisition, reconstruction, and image analysis.
  • Excellent knowledge of MR physics and programming skills in C/C++, MATLAB or Python.
  • Ideally experience in MR sequence programming (preferably on Philips MR systems).
  • Affinity with medical applications.
  • Strong communication and collaborative skills.

Your tasks:

  • To work directly with other scientists to ensure that our research studies take full advantage of the 3T & 7T MR scanners by maximizing the clinical information available in the multi-parametric MRI images (structural, functional and other quantitative read-outs) and MRS including deuterium spectroscopy.
  • To support the 7T scanners daily operation, including MRI safety trainings.
  • To develop novel sequences and data analysis methods and bring these to applications in new projects.
  • To advance the field through your own research.
  • To engage in internal education, grant writing, knowledge dissemination, and publication of results in international, recognized scientific journals.

Your position:

You will be employed for a four-year period at the DRCMR and join the ultra-high field MR group.

Salary and Terms of Employment:

Salary, pension and terms of employment are in accordance with the agreement between the Danish Regions (Danske Regioner) and the relevant professional organization. The salary depends on background education and seniority. Further supplements can be negotiated. Note that candidates coming from abroad may be eligible for tax reductions. The position is open for candidates of all nationalities. We see diversity as strength and encourage everyone regardless of gender, age, ethnicity, disabilities or religion to apply.

 

Selected Publications

Dunås T, Wåhlin A, Nyberg L, Boraxbekk C-J. 2021. Multimodal Image Analysis of Apparent Brain Age Identifies Physical Fitness as Predictor of Brain Maintenance. Cerebral Cortex. 31(7):3393-3407. https://doi.org/10.1093/cercor/bhab019

Hansen AL, Boraxbekk C-J, Petersen ET, Paulson OB, Andersen O, Siebner HR, Marsman A. 2021. Do glia provide the link between low-grade systemic inflammation and normal cognitive ageing? A 1H magnetic resonance spectroscopy study at 7 tesla. Journal of Neurochemistry. 159(1):185-196.

Nyberg L, Magnussen F, Lundquist A, Baaré W, Bartrés-Faz D, Bertram L, Boraxbekk CJ, Brandmaier AM, Drevon CA, Ebmeier K, Ghisletta P, Henson RN, Junqué C, Kievit R, Kleemeyer M, Knights E, Kühn S, Lindenberger U, Penninx BWJH, Pudas S, Sørensen Ø, Vaqué-Alcázar L, Walhovd KB, Fjell AM. 2021. Educational attainment does not influence brain aging. Proceedings of the National Academy of Sciences of the United States of America. 118(18):1-3. https://doi.org/10.1073/pnas.2101644118

Sandberg P, Boraxbekk C-J, Zogaj I, Nyberg L. 2021. Ancient Mnemonic in New Format-Episodic Memory Training With the Method of Loci in a Smart Phone Application. Journals of Gerontology - Series B Psychological Sciences and Social Sciences. 76(4):681-691. https://doi.org/10.1093/geronb/gbaa216

Vidal-Pineiro D, Wang Y, Krogsrud SK, Amlien IK, Baaré WF, Bartres-Faz D, Bertram L, Brandmaier AM, Drevon CA, Düzel S, Ebmeier K, Henson RN, Junqué C, Kievit RA, Kühn S, Leonardsen E, Lindenberger U, Madsen KS, Magnussen F, Mowinckel AM, Nyberg L, Roe JM, Segura B, Smith SM, Sørensen Ø, Suri S, Westerhausen R, Zalesky A, Zsoldos E, Walhovd KB, Fjell A. 2021. Individual variations in 'brain age' relate to early-life factors more than to longitudinal brain change. eLife. 10:1-19. https://doi.org/10.7554/eLife.69995

Lind, A., Boraxbekk, C.J., Petersen, E.T., Paulsson, O., Siebner, H., & Marsman, A. (2020). Regional myo-inositol, creatine and choline levels are higher at older age and scale negatively with visuo-spatial working memory: A cross-sectional proton MR spectroscopy study at 7 tesla on normal cognitive ageing. Journal of Neuroscience, 40(42), 8149-8159.

Nyberg, L., Boraxbekk, C.J., Eriksson Sörman, D., Hansson, P., Herlitz, A., Kauppi, K., Ljungberg, J.K., Lövheim, H., Lundquist, A., Nordin Adolfsson, A., Oudin, A., Pudas, S., Rönnlund, M., Stiernstedt, M., Sundström, A., & Adolfsson, R. (2020). Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies. Ageing Research Reviews.

Gylling AT, Bloch-Ibenfeldt M, Eriksen CS, Ziegler AK, Wimmelmann CL, Baekgaard M, Boraxbekk CJ, Siebner HR, Mortensen EL, & Kjaer M. (2020). Maintenance of muscle strength following a one-year resistance training program in older adults. Experimental Gerontology, 139.

Eskilsson, T., Fjellman-Wiklund, A., Ek Malmer, E., Stigsdotter Neely, A., Malmberg Gavelin, H., Slunga Järvholm, L., Boraxbekk, C-J. & Nordin, M.(2020). Hopeful struggling for health: Experiences of participating in computerized cognitive training and aerobic training for persons with stress-related exhaustion disorder. Scandinavian Journal of Psychology.

Friedman, B. B., Suri, S., Solé-Padullés, C., Düzel, S., Drevon, C. A., Baaré, W. F. C., Bartrés-Faz, D., Fjell, A. M., Johansen-Berg, H., Madsen, K. S., Nyberg, L., Penninx, B. W. J. H., Sexton, C., Walhovd, K. B., Zsoldos, E. & Budin-Ljøsne, I. (2020). Are People Ready for Personalized Brain Health? Perspectives of Research Participants in the Lifebrain Consortium. The Gerontologist.

Hansen, A. L., Boraxbekk, C-J., Petersen, E. T., Paulson, O. B., Siebner, H. R. & Marsman, A. (2020). Regional glia-related metabolite levels are higher at older age and scale negatively with visuo-spatial working memory: A cross-sectional proton MR spectroscopy study at 7 tesla on normal cognitive ageing. Cold Spring Harbor Protocols. 36 p., 864496.

Karalija, N., Jonassson, L., Johansson, J., Papenberg, G., Salami, A., Andersson, M., Riklund, K., Nyberg, L. & Boraxbekk, C-J. (2020). High long-term test-retest reliability for extrastriatal 11C-raclopride binding in healthy older adults.
Journal of cerebral blood flow and metabolism.

Wheeler, M. J., Green, D. J., Ellis, K. A., Cerin, E., Heinonen, I., Naylor, L. H., Larsen, R., Wennberg, P., Boraxbekk, C-J., Lewis, J., Eikelis, N., Lautenschlager, N. T., Kingwell, B. A., Lambert, G., Owen, N. & Dunstan, D. W. (2020).
Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition.
British Journal of Sports Medicine.

Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjaer, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T., Skovgaard, T., Troelsen, J., Tulle, E., Tully, M. A., van Uffelen, J. G. Z. & Viña, J. (2019). Copenhagen Consensus statement 2019: physical activity and ageing. British Journal of Sports Medicine. 53, 14, p. 856-858.

Bojsen-Møller, E., Boraxbekk, C-J., Ekblom, Ö., Blom, V. & Ekblom, M. M. (2019). Relationships between Physical Activity, Sedentary Behaviour and Cognitive Functions in Office Workers.
International Journal of Environmental Research and Public Health. 16, 23, p. 1-15, 4721.

Düzel, E., Acosta-Cabronero, J., Berron, D., Biessels, G. J., Björkman-Burtscher, I., Bottlaender, M., Bowtell, R., Buchem, M. V., Cardenas-Blanco, A., Boumezbeur, F., Chan, D., Clare, S., Costagli, M., de Rochefort, L., Fillmer, A., Gowland, P., Hansson, O., Hendrikse, J., Kraff, O., Ladd, M. E., Ronen, I., Petersen, E., Rowe, J. B., Siebner, H., Stoecker, T., Straub, S., Tosetti, M., Uludag, K., Vignaud, A., Zwanenburg, J. & Speck, O. (2019). European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND). Alzheimer's & dementia (Amsterdam, Netherlands). 11, p. 538-549.

Hedlund, M., Lindelöf, N., Johansson, B., Boraxbekk, C-J. & Rosendahl, E. (2019). Development and Feasibility of a Regulated, Supramaximal High-Intensity Training Program Adapted for Older Individuals. Frontiers in physiology. 10, p. 1-12, 590.

Holm, S. K., Madsen, K. S., Vestergaard, M., Born, A. P., Paulson, O. B., Siebner, H. R., Uldall, P. & Baaré, W. F. C. (2019). Previous glucocorticoid treatment in childhood and adolescence is associated with long-term differences in subcortical grey matter volume and microstructure. NeuroImage. Clinical. 23, p. 1-11, 101825. 

Jonasson, L. S., Nyberg, L., Axelsson, J., Kramer, A. F., Riklund, K. & Boraxbekk, C-J. (2019). Higher striatal D2-receptor availability in aerobically fit older adults but non-selective intervention effects after aerobic versus resistance training. NeuroImage. 202, p. 1-10, 116044.

Magnusson, P. O., Boer, V. O., Marsman, A., Paulson, O. B., Hanson, L. G. & Petersen, E. T. (2019). Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T.
Magnetic Resonance in Medicine. 81, 2, p. 773-780.

Månsson, K. N. T., Lindqvist, D., Yang, L. L., Svanborg, C., Isung, J., Nilsonne, G., Bergman-Nordgren, L., El Alaoui, S., Hedman-Lagerlöf, E., Kraepelien, M., Högström, J., Andersson, G., Boraxbekk, C-J., Fischer, H., Lavebratt, C., Wolkowitz, O. M. & Furmark, T. (2019). Improvement in indices of cellular protection after psychological treatment for social anxiety disorder. Translational psychiatry. 9, p. 1-10, 340.

Marsman, A. & Pol, H. H. (2019). Glutamaterge neurotransmissie. Handboek schizofreniespectrumstoornissen. 2nd udg. De Tijdstroom/Boom, Bind 2019. p. 370-385..

Malmberg Gavelin, H., Eskilsson, T., Boraxbekk, C.J., Josefsson, M., Stigsdotter Neely, A., & Slunga Järvholm L. (2018). Rehabilitation for improved cognition in patients with stress-related exhaustion disorder: RECO – a randomized clinical trial. Stress.

Boraxbekk, C.-J. (2018). Non-invasive brain stimulation and neuro-enhancement in aging. Clinical Neurophysiology, 129, 464-65.

Baruël Johansen, L., Madsen, K. S., Andersen, K. W., Madsen, K. H., Siebner, H. R. & Baaré, W. F. C. (2017) Reduced orbitofrontal functional network centrality characterizes high neuroticism across childhood and adolescence.

Stomby, A., Otten, J., Ryberg, M., Nyberg, L., Olsson, T. & Boraxbekk, C-J. (2017). A Paleolithic Diet with and without Combined Aerobic and Resistance Exercise Increases Functional Brain Responses and Hippocampal Volume in Subjects with Type 2 Diabetes. Frontiers in Aging Neuroscience. 9, 391.

Jonasson, L. S., Axelsson, J., Riklund, K. & Boraxbekk, C.-J. (2017). Simulating effects of brain atrophy in longitudinal PET imaging with an anthropomorphic brain phantom.
Physics in Medicine and Biology. 62, 13, p. 5213-5227.

Gavelin, H. M., Neely, A. S., Andersson, M., Eskilsson, T., Järvholm, L. S. & Boraxbekk, C-J. (2017). Neural activation in stress-related exhaustion: Cross-sectional observations and interventional effects.
Psychiatry Research. 269, p. 17-25.

Flodin, P., Jonasson, L. S., Riklund, K., Nyberg, L. & Boraxbekk, C.-J. (2017). Does Aerobic Exercise Influence Intrinsic Brain Activity?: An Aerobic Exercise Intervention among Healthy Old Adults.Frontiers in Aging Neuroscience. 9, p. 267.

Eskilsson, T., Slunga Järvholm, L., Malmberg Gavelin, H., Stigsdotter Neely, A. & Boraxbekk, C-J. (2017). Aerobic training for improved memory in patients with stress-related exhaustion: a randomized controlled trial. BMC Psychiatry. 17, 322, p. 1-10, 322.

Bas-Hoogendam, J. M., van Steenbergen, H., Nienke Pannekoek, J., Fouche, J. P., Lochner, C., Hattingh, C. J., Cremers, H. R., Furmark, T., Månsson, K. N. T., Frick, A., Engman, J., Boraxbekk, C.-J., Carlbring, P., Andersson, G., Fredrikson, M., Straube, T., Peterburs, J., Klumpp, H., Phan, K. L., Roelofs, K., Veltman, D. J., van Tol, M. J., Stein, D. J. & van der Wee, N. J. A. (2017). Voxel-based morphometry multi-center mega-analysis of brain structure in social anxiety disorder. NeuroImage: Clinical. 16, p. 678-688.

Jonasson, L.S., Nyberg, L., Kramer, A.F., Lundquist, A., Riklund, K., & Boraxbekk, C.-J. (2017). Aerobic exercise intervention, cognitive performance, and brain structure: Results from the physical influences on brain in aging (PHIBRA) study. Frontiers in Aging Neuroscience; 8, 336.

Boraxbekk, C.-J., Salami, A., Wåhlin, A., & Nyberg, L. (2016). Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default mode network - a multimodal approach. NeuroImage; 131, 133-141

Group Members

Naiara Demnitz

Group Leader

Sussi Larsen

External Collaborators

Prof. Erik Lykke Mortensen

Department of Public Health, Copenhagen University


Prof. Michael Kjær

Department of Clinical Medicine, Bispebjerg Hospital, University of Copenhagen


Prof. Gunhild Waldemar

Department of Neurology, Copenhagen University Hospital Rigshospitalet 


Prof. Lars Nyberg

Umeå Center for  Functional Brain Imaging