Overall research areas
Sequences and image reconstruction
Field inhomogeneity, motion and artifacts
Multi-modal data acquisition
Spectroscopy and spectroscopic imaging

Lars G. Hanson
Group leader
DRCMR, DTU Elektro
Spectroscopic imaging
Motion and correction
Signal acquisition

Mads Andersen
Post doc, DRCMR
Philips Healthcare
Motion and correction

Peter Magnusson
Senior Reserarcher
DRCMR
Spectroscopic Imaging

Kristoffer H. Madsen
Senior Researcher
DRCMR
Motion and correction

Jan Ole Pedersen
PhD student
DTU Elektro
Non-MR signals in the
MR environment

Carlos Dieste
MSc student
DTU Elektro
Motion tracking

Objectives:
The members of the “MR physics and acquisition group” at the DRCMR and DTU do research improving MR scanning, e.g. with respect to speed, robustness, sensitivity or specificity. They may also work on separate topics in other research groups. The employed methods range from fundamental physics to advanced data processing techniques needed to extract important physiological parameters from the measurements. The targets of the development include imaging, spectroscopy, and multi-modal acquisition.

The group also provides education in MRI physics and techniques at the DRCMR, the DTU and elsewhere. Educational material and software developed for this is made freely available, and is used widely internationally.

Group description:
The group members have technical backgrounds, e.g. in physics, mathematics and engineering. External collaborations are established including strong ties to departments at the Technical University of Denmark (most notably DTU Compute and Center for Magnetic Resonance, Biomedical Engineering / Medicine&Technology at DTU Elektro).

Collaborators:
DTU Center for Magnetic Resonance, Technical University of Denmark, Lyngby (DTU Elektro)
DTU Biomedical Engineering, Technical University of Denmark, Lyngby (DTU Elektro)
DTU Compute, Technical University of Denmark, Lyngby (DTU Compute)
Lund University Bioimaging Centre, Lund, Sweden
C. J. Gorter Center for Highfield MRI, Leiden University Medical Center, Holland
Imaging Sciences Institute, University Medical Center Utrecht, Holland

Selected publications:

Andersen, M., Hanson, L. G., Madsen, K. H., Wezel, J., Boer, V., van der Velden, T., van Osch, M. J. P., Klomp, D., Webb, A. G. & Versluis, M. J. Measuring motion-induced B0 -fluctuations in the brain using field probes. Magnetic Resonance in Medicine, in press, 2016.

Andersen, M, Madsen, K. H. and Hanson, L. G., Prospective motion correction for MRI using EEG-equipment
Proceedings of the 24th ISMRM conference, in press, 2016.

Magnusson, P.O, Jensen, P.R, Dyrby, T.B., Karlsson, M., Lerche, M.H. and L.G. Hanson. 3D Metabolic ex vivo sample imaging of hyperpolarized compounds using a 3D Single-Shot RARE (3D SS-RARE) sequence, combining spectral RF selectivity with undersampled spectral encoding at signal read-out. Proceedings of the 5th International DNP Symposium, 2015.

Hanson, L. G. The Ups and Downs of Classical and Quantum Formulations of Magnetic Resonance.
Anthropic Awareness: The Human Aspects of Scientific Thinking in NMR Spectroscopy and Mass Spectrometry: Edited by: C Szantay, Jr. Elsevier, Chap. 3, p. 141-171, 2015.

Andersen, M., Madsen, K. H., Hanson, L. G., Boer, V., van der Velden, T., Klomp, D., Wezel, J., Osch, M. J. V., Webb, A. G. & Versluis, M. J. Placement of field probes for stabilization of breathing-induced B0-fluctuations in the brain.
Proceedings of the ISMRM conference, p. 1015, 2015.

Andersen M, Madsen KH, Hanson LG, Boer V, van der Velden T, Klomp D, Wezel J, van Osch M, Versluis MJ. Mapping and correcting respiration-induced field changes in the brain using fluorine field probes.
Proceedings of the ISMRM/ESMRMB conference, 2014.

Lund, H., Krakauer, M., Skimminge, A., Sellebjerg, F., Garde, E., Siebner, H. R., Paulson, O. B., Hesse, D. & Hanson, L. G. Blood-brain barrier permeability of normal appearing white matter in relapsing-remitting multiple sclerosis. P L o S One. 8, 2, s. e56375, 2013.

Andersen, M; Hanson LG. A phatom-based validation framework for EEG-fMRI acquisition methods, Proceedings of the ESMRMB, 2012.

Vestergaard, M; Schulz J; Turner, R; Hanson LG. Motion tracking from gradient induced signals in electrode recordings. Proceedings of the ESMRMB, 368, 2011.

de Nijs R;Miranda MJ;Hansen LK;Hanson LG. Motion correction of single-voxel spectroscopy by independent component analysis applied to spectra from nonanesthetized pediatric subjects.
Magn Reson Med 2009, 62(5), 1147-1154.
WebSearch

Søgaard LV;Dorniok T;Hengstenberg F;Karpuk S;Vestbo J;Åkeson P;Magnusson P.
Compressed Sensing for Hyperpolarized 3He 3D ADC Measurements. Oral presentation.
Proc Intl Soc Magn Reson Med 2009, 7.

Hanson LG. Is quantum mechanics necessary for understanding magnetic resonance?
Concepts in Magnetic Resonance Part A 2008, 32A(5), 329-340.
PDF | WebSearch

Hanson LG. A graphical simulator for teaching basic and advanced MR imaging techniques.
Radiographics 2007, 27(6), e27.
PDF | WebSearch

Hanson LG;Lund TE;Hanson CG. Encoding of electrophysiology and other signals in MR images.
J Magn Reson Imaging 2007, 25(5), 1059-1066.
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Hanson LG;Lund TE;Hanson CG. Encoding and transmission of signals as RF signals for detection using an MR apparatus. WO/2005/116676, PCT/DK2005/000343 2005.
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Andersen IK;Szymkowiak A;Rasmussen CE;Hanson LG;Marstrand JR;Larsson HB;Hansen LK. Perfusion quantification using Gaussian process deconvolution.
Magn Reson Med 2002, 48(2), 351-361.
WebSearch

Hanson LG;Adalsteinsson E;Pfefferbaum A;Spielman DM. Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging.
Magn Reson Med 2000, 44(1), 10-18.
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Hanson LG;Schaumburg K;Paulson OB. Reconstruction strategy for echo planar spectroscopy and its application to partially undersampled imaging. Magn Reson Med 2000, 44(3), 412-417.
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