DRCMR Logo 300px Color
 

[EXPIRED] The Capital Region of Copenhagen is looking for a PhD candidate in Machine Learning for Neuronal Feature Identification in 3D Microscopic Imaging - DTU Compute

Do you want to join a multidisciplinary team working with a new 3D optical imaging technology and develop machine learning models to map in the brain neuronal and cellular objects, their geometry, density and organization? Are you interested in learning about 3D imaging analysis, brain anatomy, collect your own high-quality microscopic data as well as generating synthetic cellular environments to evaluate and train your model? Are you intrigued by solving challenges working with big data? Are you eager to develop innovative solutions in a groundbreaking project at the intersection of neuroimaging and machine learning? If yes, we encourage you to apply and join our team!

DTU Compute’s Section for Visual Computing is opening a PhD position in Machine Learning for Neuronal Feature Identification in 3D Microscopic Imaging. The project is financed by the Independent Research Fund Denmark – and aims at modelling neuronal anatomical compartments from 3D Light-Sheet (label-free- and fluorescence- based) microscopic imaging data. The project will also be carried out at the Danish Research Centre for MR at Copenhagen University Hospital Hvidovre, and in collaboration with IRB Barcelona: Institute for Research in Biomedicine (Barcelona, Spain).

Qualifications

  • Master's degree in visual computing, computational science and engineering, or equivalent, with focus on machine learning,
  • Experience in Python programming is highly desired,
  • Practical experience working with Machine Learning within the image processing and analysis field will be a plus,
  • Experience in experimental bioimaging will be highly valued: Interest in data collection, understanding of image data quality concepts for ensuring optimal modelling purposes. 
  • Interest in learning light-sheet based physics underpinning microscopic image contrast to be modelled, 
  • You have a good team spirit, innovative and constructive thinking, research excitement. Good English communication skills are essential.

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment 
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

You can read more about the Microstructure and Plasticity group you be part of, the Visual Computing section and the Department of Applied Mathematics and Computer Science at DTU as well as the Danish Research Centre for MR.

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. 


DTU Compute has a total staff of 400 including 100 faculty members and 130 Ph.D. students. We offer introductory courses in mathematics, statistics, and computer science to all engineering programmes at DTU and specialised courses to the mathematics, computer science, and other programmes. We offer continuing education courses and scientific advice within our research disciplines and provide a portfolio of innovation activities for students and employees.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

 

Selected Publications

Recent publications & Pre-prints 

Naiara Demnitz, Oliver J. Hulme, Hartwig R. Siebner, Michael Kjaer, Klaus P. Ebmeier, Carl-Johan Boraxbekk, Claire M. Gillan (2023). Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts, Neurobiology of Aging, Volume 131,2023, Pages 115-123, ISSN 0197-4580,IF 3.7.

TH Siebner, JD Hove, CF Madelung, OJ Hulme, F Bendtsen, HR Siebner, Flemming Bendtsen, Mads Barløse (2024). No difference in postprandial mesenteric blood flow between healthy younger and elderly individuals, Scientific Reports 14 (1), 8689.

TS Hjerresen, M Bentz, AB Nejad, E Raffin, KW Andersen, OJ Hulme, Hartwig Roman Siebner, Kerstin Jessica Plessen. Performing well but not appreciating it–A trait feature of anorexia nervosa. JCPP advances 4 (1), e12194.

Oliver Hulme, Arne Vanhoyweghen, Colm Connaughton, Ole Peters, Simon Steinkamp, Alexander Adamou, Dominik Baumann, Vincent Ginis, Bert Verbruggen, James Price, and Benjamin Skjold (2023). Reply to “The Limitations of Growth-Optimal Approaches to Decision Making Under Uncertainty”. Econ Journal Watch, 20(2) p335-348.

Hulme Oliver J., Roulston Barrie, Overgaard Morten (2023). Does report modality modulate psychophysical sensitivity? The jury remains out. Frontiers in Psychology, 14, https://www.frontiersin.org/articles/10.3389/fpsyg.2023.1226588.

Thorup AAE,… Hulme OJ, … Nordentoft M (2022). The Danish High-Risk and Resilience Study-VIA 15 - A Study Protocol for the Third Clinical Assessment of a Cohort of 522 Children Born to Parents Diagnosed With Schizophrenia or Bipolar Disorder and Population-Based Controls. Frontiers in Psychiatry.

Lopez-Yepez JS, Martin J, Hulme OJ, Kvitsiani D. (2021). A normative account of choice history effects in mice and humans. PloS Computational Biology.

Lopez-Yepez JS, Martin J, Hulme OJ, Kvitsiani D. (2021)
A normative account of choice history effects in mice and humans
PLoS Computational Biology

Meder D, Rabe F, Morville T, Madsen KH, Koudahl MT, Dolan RJ, Siebner HR, Hulme OJ. (2021)
Ergodicity-breaking reveals time optimal economic behavior in humans
PLoS Computational Biology

Morville T, Friston KJ, Burdakov D, Siebner HR, Hulme OJ. (Pre-print)
The Homeostatic Logic of Reward
bioRxiv, doi.org/10.1101/242974.

Morville T, Madsen K, Siebner HR, Hulme OJ. (2021)
Reward signaling in brainstem nuclei under glycemic flux
PloS One

Hulme, OJ, Wagenmakers EJ, Damkier P, Madelung CF, Siebner HR, Helweg-Larsen J, Gronau Q, Benfield TL, Madsen KH. (2021) A Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with COVID-19.
PloS One. doi.org/10.1371/journal.pone.0245048

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizau J, Hulme OJ, Billig AJ., Litvak V, Price CJ., Moran RJ., Costello A, Pillay D, Lambert C. (2020)
Effective immunity and second waves: a dynamic causal modelling study
Wellcome Open Res2020, 5:204 (doi.org/10.12688/wellcomeopenres.16253.2)

van der Vegt JPM, Hulme OJ, Madsen KH, Buhmann C, Bloem BR, Münchau A, Helmich RC, Siebner HR (2020)
Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson’s disease
NeuroImage Clinical

Faranda D, Castillo IP, Hulme OJ, Jezequel A, Lamb J, Sato Y, Thompson E, (2020)                                                                         
Asymptotic estimates of SARS-CoV-2 infection counts and their sensitivity to stochastic perturbation
Chaos. 2020;30(5):051107. doi:10.1063/5.0008834

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizau J, Hulme OJ, Billig AJ, Litvak V, Price CJ, Moran RJ., Lambert C. (2020)
Second waves, social distancing, and the spread of COVID-19 across America.
Wellcome Open Res 2020, 5:103 (doi.org/10.12688/wellcomeopenres.15986.1)

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizau J, Hulme OJ, Billig AJ, Litvak V, Price CJ, Moran RJ, Lambert C. (2020)
Dynamic causal modelling of COVID-19.
Wellcome Open Res 2020, 5:89

Friston KJ, Parr T, Zeidman P, Razi A, Flandin G, Daunizau J, Hulme OJ, Billig AJ., Litvak V, Price CJ., Moran RJ., Costello A, Pillay D, Lambert C. (2020)
Testing and tracking in the UK: A dynamic causal modelling study
Wellcome Open Research 5 (144), 144  

Hulme OJ, Morville T, Gutkin B. (2019)
Neurocomputational Theories of Homeostatic Control
Physics of Life Reviews, Jul 19. pii: S1571-0645(19)30100-9. doi: 10.1016/j.plrev.2019.07.005  

Hulme OJ, Webb EJ, Sebald A. (2019)
An Introduction to Physiological Economics
Handbook of Research Methods and Applications in Experimental Economics, Edward Elgar Publishing. 

Hulme OJ, Kvitsiani D. (2019)
Extending Models of How Foraging Works: Uncertainty, Controllability, and Survivability
Behavioral and Brain Sciences 2019 Jan;42:e43. doi: 10.1017/S0140525X18002017

Hallsson BG, Siebner HR, Hulme OJ. (2018)
Fairness, fast and slow: A review of dual process models of fairness
Neuroscience and Biobehavioral Reviews. Jun;89:49-60. doi: 10.1016/j.neubiorev.2018.02.016.

Christensen BJ, Schmidt JB, Nielsen MS, Tækkerd L, Holm L, Lunn S, Brediee WLP, Ritz C, Holst JJ, Hansen T, Hilbert A, le Roux CW, Hulme OJ, Siebner HR, Morville T, Naver L, Floyd, AK, Sjödin A. (2018)
Patient profiling for success after weight loss surgery: An interdisciplinary study protocol
Contemporary Clinical Trials Communications. Feb 17;10:121-130. doi: 10.1016/j.conctc.2018.02.002.

Larsen KM, Mørup M,  Birknow MR, Fischer E, Hulme OJ,  Vangkilde A, Schmock H, Baaré WF, Didriksen M, Olsen L, Werge T, Siebner HR, Garrido MI. (2018)
Altered auditory processing and top-down connectivity in 22q11.2 Deletion Syndrome
Schizophrenia Research. Jan 30. pii: S0920-9964(18)30048-3. doi: 10.1016/j.schres.2018.01.026.

Meder D, Kolling N, Verhagen L, Wittmann MK, Scholl J, Madsen KH, Hulme OJ, Behrens TEJ, Rushworth MFS. (2017)
Simultaneous representation of a spectrum of dynamically changing value estimates during decision making
Nature Communications. Dec 5;8(1):1942. doi: 10.1038/s41467-017-02169-w.

Friis-Olivarius M, Hulme OJ, Skov M, Ramsøy TZ, Siebner HR. (2017)
Imaging the Creative Unconscious: Reflexive Neural Responses to Objects in the Visual and Parahippocampal Region Predicts State and Trait Creativity
Scientific Reports. Oct 31;7(1):14420. doi: 10.1038/s41598-017-14729-7.

Group Members

Oliver Hulme

Group Leader

Simon Steinkamp

Maria Elisabeth Catharina van der Weij

External Collaborators

Prof. Derek Byrne


Dr. Ole Peters


Dr. Alex Adamou


Dr. Mark Kirstein


Dr. Yonatan Berman


Prof. Sten Madsbad


Assoc. Prof. Tobias Andersen


Assoc. Prof. Christoffer Clemmensen


Postdoc Claus Brandt


Prof. Duda Kvitsiani


Adam Goldstein