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Wednesday, 28 October 2020 10:16

Understanding normal cognitive ageing

Article published in the Journal of Neuroscience

DRCMR Researchers recently published the article ‘Regional Myo-Inositol, Creatine, and Choline Levels Are Higher at Older Age and Scale Negatively with Visuospatial Working Memory: A Cross-Sectional Proton MR Spectroscopy Study at 7 Tesla on Normal Cognitive Ageing’ in the Journal of Neuroscience, doi.org/10.1523/JNEUROSCI.2883-19.2020.

Understanding normal cognitive ageing is a vital step toward identifying the distinguishing features of successful and pathologic ageing. Lind et al. found that glia-related metabolites are higher in older individuals in hippocampus, thalamus, and frontal brain regions. Furthermore, higher levels of glia-related metabolites were related to lower cognitive performance. This study emphasizes the role of glial cells across the brain in normal cognitive ageing and identifies a set of biomarkers that may help describe cognitive ageing.

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 You can find the article as a pdf file by clicking HERE.