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Thursday, 24 April 2025 12:08

CoBS 2024

held in December 2024

CoBS 2024 billede 3

25 trainees from near and far spent four intense days listening to expert presentations in the morning from DRCMR and external lecturers, and practical lab training in the afternoon.

We went through three stimulation modalities and their combination with neuroimaging and application in clinical setting.

To round off the week, DRCMR hosted the CoBS Symposium featuring renowed local and international speakers. This year's speaker list included:

Salvatore Bertino
Rikke H. Kofoed
Estelle Raffin
Jean-Francois Aubry
Saša Filipovic
Til Ole Bergmann
Laura De Herde
Mark Hallett
Lasse Christiansen

 

Selected Publications

Madsen MAJ, Wiggermann V, Bramow S, Christensen JR, Sellebjerg F, Siebner HR. 2021. Imaging cortical multiple sclerosis lesions with ultra-high field MRI. NeuroImage. Clinical. 32:1-14. https://doi.org/10.1016/j.nicl.2021.102847

Chow HH, Talbot J, Marstrand L, Lundell H, Roman Siebner H, Bach Søndergaard H, Sellebjerg F. 2021. Smoking, cardiovascular risk factors and LRP2 gene variation: Associations with disease severity, cognitive function and brain structure in primary progressive multiple sclerosis. Multiple Sclerosis and Related Disorders. 56:1-7. https://doi.org/10.1016/j.msard.2021.103296

Ruiu E, Dubbioso R, Madsen KH, Svolgaard O, Raffin E, Andersen KW, Karabanov AN, Siebner HR. 2020. Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis. Frontiers in Neurology. 11:1-10. Available from: 10.3389/fneur.2020.00193

Bauer C, Dyrby TB, Sellebjerg F, Madsen KS, Svolgaard O, Blinkenberg M, Siebner HR, Andersen KW. 2020. Motor fatigue is associated with asymmetric connectivity properties of the corticospinal tract in multiple sclerosis. NeuroImage. Clinical. 28:1-12. Available from: 10.1016/j.nicl.2020.102393

Lundell, H., Svolgaard, O., Dogonowski, A-M., Romme Christensen, J., Selleberg, F., Soelberg Sørensen, P., Blinkenberg, M., Siebner, H. R. & Garde, E.
Spinal cord atrophy in anterior-posterior direction reflects impairment in multiple sclerosis.
Acta Neurologica Scandinavica. 136, 4, p. 330-337, 2017.

Schreiber K, Magyari M, Sellebjerg F, Iversen P, Garde E, Gøbel Madsen C, Börnsen L, Christensen JR, Ratzer R, Siebner HR, Laursen B, Soelberg Sorensen P. High-dose erythropoietin in patients with progressive multiple sclerosis: a randomized, placebo controlled, phase 2 trial. Mult Scler 2016: Epub ahead of print.

Dogonowski AM, Blinkenberg M, Paulson OB, Sellebjerg F, Soelberg Sørensen P, Siebner HR, Madsen KH. Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis. J Neurol Neurosurg Psychiatry 2016;87:912-914.

Ratzer R, Iversen P, Börnsen L, Dyrby T, Romme Christensen J, Ammitzbøll C, Madsen C, Garde E, Lyksborg M, Andersen B, Hyldstrup L, Soelberg Sørensen P, Siebner HR, Sellebjerg F. Monthly oral methylprednisolone pulse treatment in progressive multiple sclerosis. Mult Scler 2016;22:926-934.

Voldsgaard A, Bager P, Garde E, Åkeson P, Leffers AM, Kapel C, Roepstorff A, Thamsborg SM, Melbye M, Siebner H, Søndergaard HB, Sellebjerg F, Soelberg Sørensen P. Trichuris suis ova therapy in relapsing multiple sclerosis is safe but without signals of beneficial effect. Mult Scler 2015;21:1723-1729.

Weier K, Banwell B, Cerasa A, Collins DL, Dogonowski AM, Lassmann H, Quattrone A, Sahraian MA, Siebner HR, Sprenger T. The role of the cerebellum in multiple sclerosis. Cerebellum 2015;14:364-374.

Christensen JR, Ratzer R, Börnsen L, Lyksborg M, Garde E, Dyrby TB, Siebner HR, Sorensen PS, Sellebjerg F. Natalizumab in progressive MS: Results of an open-label, phase 2A, proof-of-concept trial. Neurology 2014;82:1499-1507. 

Lyksborg M, Siebner HR, Sørensen PS, Blinkenberg M, Parker GJM, Dogonowski A, Garde E, Larsen R, Dyrby TB. Secondary progressive and relapsing remitting multiple sclerosis leads to motor-related decreased anatomical connectivity. PLOS ONE 2014;9, e95540.

Christensen JR, Ratzer R, Börnsen L, Lyksborg M, Garde E, Dyrby TB, Siebner HR, Sørensen PS, Sellebjerg F. Natalizumab in progressive MS – results of an open-label phase 2A proof-of- concept trial. Neurology 2014;82:1499-1507. 

Dogonowski, A.-M., Andersen, K. W., Madsen, K. H., Sørensen, P. S., Paulson, O. B., Blinkenberg, M., & Siebner, H. R. Multiple sclerosis impairs regional functional connectivity in the cerebellum. NeuroImage: Clinical, 2014, 4:130–138.

Group Members

Hartwig R. Siebner

Group Leader

Henrik Lundell

Vanessa Wiggermann

Mads Alexander Just Madsen

Show all group members (14)

External Collaborators

Consultant Anne-Mette Leffers

Centre for Functional and Diagnostic Imaging, Copenhagen University Hospital Hvidovre, Denmark


Consultant Camilla Gøbel Madsen

Centre for Functional and Diagnostic Imaging, Copenhagen University Hospital Hvidovre, Denmark


Professor Per Soelberg Sørensen, Professor Finn Sellebjerg, Morten Blinkenberg

and other physicians from the Danish Multiple Sclerosis Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Denmark.


Kathrine S. Madsen,

Faculty of Health and Technology, Metrolitan University College


Associate Professor Morten Mørup

Cognitive Systems, DTU Compute, Technical University of Denmark


Jesper Bencke

Gait Laboratory, Copenhagen University Hospital Hvidovre, Denmark


Associate Professor Itamar Ronen

Leiden University Medical Center, Leiden, The Netherlands


Professor Christian Dettmers

Kliniken Schmieder, Konstanz, Germany