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Workshop on Applications of Human Ultra-High Field MRI, May 2010

The workshop on applications of MRI at ultra-high magnetic fields described below was succesfully held. We thank the 85 attendants for an excellent and lively meeting. The speakers in particular gave remarkable presentations on this field in rapid development. Follow link for a brief review.

In spring 2010 many MR scientists and clinicians will be in Stockholm for the ISMRM/ESMRMB meeting taking place May 1st-7th. While being in Scandinavia, we encourage those with special interest in ultra-high field MRI studies to take the opportunity to stop in Copenhagen on the way home for a 1½ day symposium. The focus will be on scientific and clinical applications of MR in humans at magnetic fields of 7 tesla and above (download flyer).

The meeting in Stockholm ends at noon May 7th and the meeting in Copenhagen starts the following day, also at noon. This gives you the possibility to enjoy the Scandinavian atmosphere in Stockholm and/or Copenhagen between the two meetings. The Stockholm-Copenhagen flight takes one hour only. There are several departures every day.

  • May 8th, 12 noon - 1pm: Registration and lunch (remember to sign up).
  • May 8th, 1pm - 5pm: Scientific sessions, followed by conference dinner in the evening.
  • May 9th, 9am -3pm: Scientific sessions (lunch from 12.30 to 1.30)

Further updates will be published on this page: http://www.drcmr.dk/UHF2010. Questions are addressed by the conference secretary Dorte Frejwald.

Program
We are proud to present some of the most outstanding experts in the field of ultra-high field imaging applications. Preliminary list of confirmed speakers and session overview:

Saturday, early afternoon session:

  • Siegfried Trattnig, Medical University of Vienna, Austria: High resolution morphological, compositional and metabolic imaging in the musculoskeletal system by ultra-high field
  • Mark Ladd, University Duisburg-Essen, Germany. Advances in Ultra-High Field Body Imaging
  • Sarah J. Nelson, University of California, San Francisco, USA: Clinical applications at ultra-high field.

Saturday, late afternoon session:

  • Marta Bianciardi, NIH, USA: Spontaneous signal fluctuations in human fMRI at high magnetic fields.
  • Robert Turner, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany: Multimodal imaging

Sunday, early morning session:

  • Jeff Duyn, NIH, USA: Anatomical MRI based on magnetic susceptibility contrast.
  • Fernando E. Boada, University of Pittsburg, USA: Monitoring Ion Homeostasis with Sodium MRI (sMRI).

Sunday, late morning session:

  • Rolf Gruetter, University of Lausanne, Switzerland. In vivo metabolism studies at ultra-high field.
  • Oliver Speck, Otto-von-Guericke-Universität Magdeburg, Germany: Towards fMRI of subcortical structures at high field.

Sunday, afternoon session:

  • Kamil Ugurbil, University of Minnesota, USA: fMRI of the visual system at ultra-high field
  • Lawrence Wald, Massachusetts General Hospital, USA: Control of CBF at the laminar level.

Confirmed chairpersons:

  • Ewald Moser, Medical University of Vienna, Austria.
  • Stefan Posse, University of New Mexico, USA.
  • Peter Bandettini, NIH, Maryland, USA

Venue
The meeting is held at the remarkably pleasant Helene Elsass Centre situated beautifully just north of the Danish Capital Copenhagen (map). Connections from central Copenhagen to Ordrup station are good (trains every 10 minutes, duration 20 minutes, 5 minutes walk to  the venue).

See "Accommodation" below for travel from airport to recommended hotel close to venue.

Meals
The sponsored conference dinner on Saturday and the lunches on Saturday and Sunday are included in the registration fee. Please indicate at registration whether you plan to attend. Please send a mail in advance if you have special dietary requests.

Accommodation
The attendants are asked to arrange and pay for accommodation themselves (except for invited speakers and chairmen). Accommodation and transport expenses are not included in the attendance fee. The Hellerup Park Hotel is recommended. Rooms are offerered ranging from approximately $200 to $280 per night. Please book before March 1st, if possible via mail to . Please specify reference number 63245 when booking.

The easiest travel from the Airport to  Hellerup Park Hotel is via train to Hellerup station (30 minutes, leaving every 10 minutes), and via taxi from there (app. 8 EUR).

The Wonderful Copenhagen Agency can provide further options and advice regarding booking and stay.

Currency
The currency in Denmark is "kroner", DKK (approximately 1/7.5 EUR or 1/5 USD). Visa and MasterCards are widely accepted, also in most taxis.

Sponsors
Due to the generosity of the sponsors, the registration fee is kept modest:

  • GE Healthcare
  • Philips Healthcare
  • Siemens Healthcare
  • Ludvig and Sara Elsass Foundation

Registration
Registration is performed by filling in the form below, and by paying the attendance fee in full via PayPal. Registration is only considered complete when payment is received. The deadline is April 15th (noon, central European time). Questions are addressed by the conference secretary Dorte Frejwald.

Attendance fee and payment
The attendance fee is EUR 150. Credit card payments and bank transfers can be performed via PayPal, which is the only supported payment option. Payment charges are included in the attendance fee, so please assign these to "seller" in the registration process (there is no refund, if you choose not to).

The mentioned meals are included in the conference fee. Guests and spouses are welcome at the conference dinner (DKR 500 per extra person paid on site).

Cancellation and refund policy
The paid amount is refunded in total, if written cancellation is received within two weeks after registration. Fifty percent of the registration fee is returned if cancellation is received before the registration deadline. After that, no refund is provided.

Local organising committee

  • Lars G. Hanson (program chair), Danish Research Centre for MR and DTU, Copenhagen, Denmark.
  • Olaf B. Paulson (chairman), Danish Research Centre for MR, Copenhagen, Denmark.
  • Hartwig R. Siebner, Danish Research Centre for MR, Copenhagen, Denmark.
  • Freddy Ståhlberg, Lund University, Sweden.
  • Carsten Thomsen, Rigshospitalet, Copenhagen, Denmark.
  • Leif Østergaard, Center for Functionally Integrative Neuroscience, Århus, Denmark.
  • Per Åkeson, Danish Research Centre for MR, Copenhagen, Denmark.

Practical issues and registration: Form is no longer available

The workshop on applications of MRI at ultra-high magnetic fields described below was succesfully held. We thank the 85 attendants for an excellent and lively meeting. The speakers in particular gave remarkable presentations on this field in rapid development. Follow link for a brief review.

In spring 2010 many MR scientists and clinicians will be in Stockholm for the ISMRM/ESMRMB meeting taking place May 1st-7th. While being in Scandinavia, we encourage those with special interest in ultra-high field MRI studies to take the opportunity to stop in Copenhagen on the way home for a 1½ day symposium. The focus will be on scientific and clinical applications of MR in humans at magnetic fields of 7 tesla and above (download flyer).

The meeting in Stockholm ends at noon May 7th and the meeting in Copenhagen starts the following day, also at noon. This gives you the possibility to enjoy the Scandinavian atmosphere in Stockholm and/or Copenhagen between the two meetings. The Stockholm-Copenhagen flight takes one hour only. There are several departures every day.

  • May 8th, 12 noon - 1pm: Registration and lunch (remember to sign up).
  • May 8th, 1pm - 5pm: Scientific sessions, followed by conference dinner in the evening.
  • May 9th, 9am -3pm: Scientific sessions (lunch from 12.30 to 1.30)

Further updates will be published on this page: http://www.drcmr.dk/UHF2010. Questions are addressed by the conference secretary Dorte Frejwald.

Program
We are proud to present some of the most outstanding experts in the field of ultra-high field imaging applications. Preliminary list of confirmed speakers and session overview:

Saturday, early afternoon session:

  • Siegfried Trattnig, Medical University of Vienna, Austria: High resolution morphological, compositional and metabolic imaging in the musculoskeletal system by ultra-high field
  • Mark Ladd, University Duisburg-Essen, Germany. Advances in Ultra-High Field Body Imaging
  • Sarah J. Nelson, University of California, San Francisco, USA: Clinical applications at ultra-high field.

Saturday, late afternoon session:

  • Marta Bianciardi, NIH, USA: Spontaneous signal fluctuations in human fMRI at high magnetic fields.
  • Robert Turner, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany: Multimodal imaging

Sunday, early morning session:

  • Jeff Duyn, NIH, USA: Anatomical MRI based on magnetic susceptibility contrast.
  • Fernando E. Boada, University of Pittsburg, USA: Monitoring Ion Homeostasis with Sodium MRI (sMRI).

Sunday, late morning session:

  • Rolf Gruetter, University of Lausanne, Switzerland. In vivo metabolism studies at ultra-high field.
  • Oliver Speck, Otto-von-Guericke-Universität Magdeburg, Germany: Towards fMRI of subcortical structures at high field.

Sunday, afternoon session:

  • Kamil Ugurbil, University of Minnesota, USA: fMRI of the visual system at ultra-high field
  • Lawrence Wald, Massachusetts General Hospital, USA: Control of CBF at the laminar level.

Confirmed chairpersons:

  • Ewald Moser, Medical University of Vienna, Austria.
  • Stefan Posse, University of New Mexico, USA.
  • Peter Bandettini, NIH, Maryland, USA

Venue
The meeting is held at the remarkably pleasant Helene Elsass Centre situated beautifully just north of the Danish Capital Copenhagen (map). Connections from central Copenhagen to Ordrup station are good (trains every 10 minutes, duration 20 minutes, 5 minutes walk to  the venue).

See "Accommodation" below for travel from airport to recommended hotel close to venue.

Meals
The sponsored conference dinner on Saturday and the lunches on Saturday and Sunday are included in the registration fee. Please indicate at registration whether you plan to attend. Please send a mail in advance if you have special dietary requests.

Accommodation
The attendants are asked to arrange and pay for accommodation themselves (except for invited speakers and chairmen). Accommodation and transport expenses are not included in the attendance fee. The Hellerup Park Hotel is recommended. Rooms are offerered ranging from approximately $200 to $280 per night. Please book before March 1st, if possible via mail to . Please specify reference number 63245 when booking.

The easiest travel from the Airport to  Hellerup Park Hotel is via train to Hellerup station (30 minutes, leaving every 10 minutes), and via taxi from there (app. 8 EUR).

The Wonderful Copenhagen Agency can provide further options and advice regarding booking and stay.

Currency
The currency in Denmark is "kroner", DKK (approximately 1/7.5 EUR or 1/5 USD). Visa and MasterCards are widely accepted, also in most taxis.

Sponsors
Due to the generosity of the sponsors, the registration fee is kept modest:

  • GE Healthcare
  • Philips Healthcare
  • Siemens Healthcare
  • Ludvig and Sara Elsass Foundation

Registration
Registration is performed by filling in the form below, and by paying the attendance fee in full via PayPal. Registration is only considered complete when payment is received. The deadline is April 15th (noon, central European time). Questions are addressed by the conference secretary Dorte Frejwald.

Attendance fee and payment
The attendance fee is EUR 150. Credit card payments and bank transfers can be performed via PayPal, which is the only supported payment option. Payment charges are included in the attendance fee, so please assign these to "seller" in the registration process (there is no refund, if you choose not to).

The mentioned meals are included in the conference fee. Guests and spouses are welcome at the conference dinner (DKR 500 per extra person paid on site).

Cancellation and refund policy
The paid amount is refunded in total, if written cancellation is received within two weeks after registration. Fifty percent of the registration fee is returned if cancellation is received before the registration deadline. After that, no refund is provided.

Local organising committee

  • Lars G. Hanson (program chair), Danish Research Centre for MR and DTU, Copenhagen, Denmark.
  • Olaf B. Paulson (chairman), Danish Research Centre for MR, Copenhagen, Denmark.
  • Hartwig R. Siebner, Danish Research Centre for MR, Copenhagen, Denmark.
  • Freddy Ståhlberg, Lund University, Sweden.
  • Carsten Thomsen, Rigshospitalet, Copenhagen, Denmark.
  • Leif Østergaard, Center for Functionally Integrative Neuroscience, Århus, Denmark.
  • Per Åkeson, Danish Research Centre for MR, Copenhagen, Denmark.

Practical issues and registration: Form is no longer available

Selected Publications

Siebner, Thomas Hartwig, Stefan Fuglsang, Christopher Fugl Madelung, Annemette Løkkegaard, Flemming Bendtsen, Jens Dahlgaard Hove, Morten Damgaard, Jan Lysgård Madsen, and Hartwig Roman Siebner. “Gastric Emptying Is Not Delayed and Does Not Correlate With Attenuated Postprandial Blood Flow Increase in Medicated Patients With Early Parkinson’s Disease.” Frontiers in Neurology 13 (2022). https://www.frontiersin.org/article/10.3389/fneur.2022.828069.

Madelung, Christopher F., David Meder, Søren A. Fuglsang, Marta M. Marques, Vincent O. Boer, Kristoffer H. Madsen, Esben T. Petersen, Anne-Mette Hejl, Annemette Løkkegaard, and Hartwig R. Siebner. “Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson’s Disease.” Movement Disorders 37, no. 3 (2022): 479–89. https://doi.org/10.1002/mds.28945.

Siebner, Thomas Hartwig, Christopher Fugl Madelung, Flemming Bendtsen, Annemette Løkkegaard, Jens Dahlgaard Hove, and Hartwig Roman Siebner. “Postprandial Increase in Mesenteric Blood Flow Is Attenuated in Parkinson’s Disease: A Dynamic PC-MRI Study.” Journal of Parkinson’s Disease 11, no. 2 (January 1, 2021): 545–57. https://doi.org/10.3233/JPD-202341.

Herz, Damian M., David Meder, Julia A. Camilleri, Simon B. Eickhoff, and Hartwig R. Siebner. “Brain Motor Network Changes in Parkinson’s Disease: Evidence from Meta-Analytic Modeling.” Movement Disorders 36, no. 5 (2021): 1180–90. https://doi.org/10.1002/mds.28468.

Lohse, Allan, David Meder, Silas Nielsen, Anders Elkjær Lund, Damian M Herz, Annemette Løkkegaard, and Hartwig R Siebner. “Low-Frequency Transcranial Stimulation of Pre-Supplementary Motor Area Alleviates Levodopa-Induced Dyskinesia in Parkinson’s Disease: A Randomized Cross-over Trial.” Brain Communications 2, no. 2 (July 1, 2020): fcaa147. https://doi.org/10.1093/braincomms/fcaa147.

Haagensen, Brian N., Damian M. Herz, David Meder, Kristoffer H. Madsen, Annemette Løkkegaard, and Hartwig R. Siebner. “Linking Brain Activity during Sequential Gambling to Impulse Control in Parkinson’s Disease.” NeuroImage: Clinical 27 (January 1, 2020): 102330. https://doi.org/10.1016/j.nicl.2020.102330.

Betts, Matthew J., Evgeniya Kirilina, Maria C. G. Otaduy, Dimo Ivanov, Julio Acosta-Cabronero, Martina F. Callaghan, Christian Lambert, et al. “Locus Coeruleus Imaging as a Biomarker for Noradrenergic Dysfunction in Neurodegenerative Diseases.” Brain 142, no. 9 (September 1, 2019): 2558–71. https://doi.org/10.1093/brain/awz193.

Meder, David, Damian Marc Herz, James Benedict Rowe, Stéphane Lehéricy, and Hartwig Roman Siebner. “The Role of Dopamine in the Brain - Lessons Learned from Parkinson’s Disease.” NeuroImage, Mapping diseased brains, 190 (April 15, 2019): 79–93. https://doi.org/10.1016/j.neuroimage.2018.11.021.

Irmen, Friederike, Andreas Horn, David Meder, Wolf-Julian Neumann, Philip Plettig, Gerd-Helge Schneider, Hartwig Roman Siebner, and Andrea A. Kühn. “Sensorimotor Subthalamic Stimulation Restores Risk-Reward Trade-off in Parkinson’s Disease.” Movement Disorders 34, no. 3 (2019): 366–76. https://doi.org/10.1002/mds.27576.

Meder, David, and Hartwig Roman Siebner. “Spectral Signatures of Neurodegenerative Diseases: How to Decipher Them?” Brain 141, no. 8 (August 1, 2018): 2241–44. https://doi.org/10.1093/brain/awy195.

Lehericy, Stéphane, David E. Vaillancourt, Klaus Seppi, Oury Monchi, Irena Rektorova, Angelo Antonini, Martin J. McKeown, et al. “The Role of High-Field Magnetic Resonance Imaging in Parkinsonian Disorders: Pushing the Boundaries Forward.” Movement Disorders 32, no. 4 (April 1, 2017): 510–25. https://doi.org/10.1002/mds.26968.

Correia, M. M., Rittman, T., Barnes, C. L., Coyle-Gilchrist, I. T., Ghosh, B., Hughes, L. E. & Rowe, J. B.
Towards accurate and unbiased imaging-based differentiation of Parkinson's disease, progressive supranuclear palsy and corticobasal syndrome.
Brain communications. 2, 1, p. 1-18, fcaa051. 2020.

Kaalund, S. S., Passamonti, L., Allinson, K. S. J., Murley, A. G., Robbins, T. W., Spillantini, M. G. & Rowe, J. B.
Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity.
Acta neuropathologica communications. 8, 1, p. 1-11, 11. 2020.

van der Vegt, J. P. M., Hulme, O. J., Madsen, K. H., Buhmann, C., Bloem, B. R., Münchau, A., Helmich, R. C. & Siebner, H. R.
Dopamine agonist treatment increases sensitivity to gamble outcomes in the hippocampus in de novo Parkinson's disease.
NeuroImage. Clinical. 28, p. 1-8, 102362. 2020.

Dogonowski, A. M., Andersen, K. W., Sellebjerg, F., Schreiber, K., Madsen, K. H. & Siebner, H. R.
Functional neuroimaging of recovery from motor conversion disorder: A case report.
NeuroImage. 190, p. 269-274, 2019.

Dubbioso, R., Manganelli, F., Siebner, H. R. & Di Lazzaro, V.
Fast Intracortical Sensory-Motor Integration: A Window Into the Pathophysiology of Parkinson's Disease.
Frontiers in Human Neuroscience. 13, p. 1-14, 111. 2019.

van Eimeren, T., Antonini, A., Berg, D., Bohnen, N., Ceravolo, R., Drzezga, A., Höglinger, G. U., Higuchi, M., Lehericy, S., Lewis, S., Monchi, O., Nestor, P., Ondrus, M., Pavese, N., Peralta, M. C., Piccini, P., Pineda-Pardo, J. Á., Rektorová, I., Rodríguez-Oroz, M., Rominger, A., Seppi, K., Stoessl, A. J., Tessitore, A., Thobois, S., Kaasinen, V., Wenning, G., Siebner, H. R., Strafella, A. P. & Rowe, J. B.
Neuroimaging biomarkers for clinical trials in atypical parkinsonian disorders: Proposal for a Neuroimaging Biomarker Utility System.
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 301-309, 2019.

Siebner, Hartwig R., David Meder, and Damian M. Herz. “FMRI in Parkinson’s Disease.” In FMRI: Basics and Clinical Applications, edited by Stephan Ulmer and Olav Jansen, 417–31. Cham: Springer International Publishing, 2020. https://doi.org/10.1007/978-3-030-41874-8_26

Thomsen, B. L. C., Herz, D. M., Siebner, H. R. & Løkkegaard, A.
Dyskinesier ved Parkinsons sygdom: opdatering om nye billeddannende metoder og behandlingsmuligheder.
Ugeskrift for Laeger. 12, 2017, p. 2-6, 2017.

Lehéricy, S., Vaillancourt, D. E., Seppi, K., Monchi, O., Rektorova, I., Antonini, A., McKeown, M. J., Masellis, M., Berg, D., Rowe, J. B., Lewis, S. J. G., Williams-Gray, C. H., Tessitore, A., Siebner, H. R. & International Parkinson and Movement Disorder Society -Neuroimaging Study Group.
The role of high-field magnetic resonance imaging in parkinsonian disorders: Pushing the boundaries forward.
Movement disorders. 32, 4, p. 510-525, 2017.

Løkkegaard A, Herz DM, Haagensen BN, Lorentzen AK, Eickhoff SB, Siebner HR (2016) Altered sensorimotor activation patterns in idiopathic dystonia - an activation likelihood estimation meta-analysis of functional brain imaging studies. Hum Brain Mapp 37:547-557.

Herz DM,  Haagensen BN, Nielsen SH, Madsen KH, Løkkegaard A, Siebner HR (2016) Resting-state connectivity predicts levodopa-induced dyskinesias in Parkinson’s disease. Mov Disord 31:521-529.

Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A, Siebner HR (2015) Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain 138:1658-1666.

Herz DM, Haagensen BN,Christensen MS, Madsen KH, Rowe J, Løkkegaard A, Siebner HR (2014) The acute brain response to levodopa heralds dyskinesias in Parkinson’s disease. Ann Neurol 75:829-836.

Herz DM, Eickhoff SB, Løkkegaard A, Siebner HR (2014) Functional neuroimaging of motor control in Parkinson’s disease: A meta-analysis. Hum Brain Mapp 35:3227-3237. 

van der Vegt JPM, Hulme OJ, Zittel S, Madsen KH, Weiss MM, Buhmann C, Bloem BR, Münchau A, Siebner HR (2013) Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson’s disease. Brain 136:1192-1203.

 

 

Group Members

David Meder

Group Leader

Hartwig R. Siebner

Yufei Song

Jiahua Xu

Show all group members (21)

External Collaborators

Assoc. Prof. Annemette Løkkegaard

Copenhagen University Hospital Bispebjerg


Damian M. Herz, MD, PhD

Nuffield Department of Clinical Neurosciences
University of Oxford


Prof. Stéphane Lehericy, MD, PhD

Institut du Cerveau et de la Moelle épinière – ICM, 
Centre de NeuroImagerie de Recherche – CENIR, Sorbonne Universités, Paris


Prof. James Rowe

Behavioural and Clinical Neuroscience Institute
Dept. of Clinical Neurosciences, University of Cambridge


Prof. Angela Cenci Nilsson

Lund University


Prof. Andrea Kühn,

Charité - Universitätsmedizin Berlin
Movement Disorders and Neuromodulation Section


Mads Barløse,

Copenhagen University Hospital Hvidovre


Prof. Poul Jennum

Rigshospitalet, Neurocentre
Department of Clinical Medicine


Prof. Ray Dolan

University College London - Imaging Neuroscience
UCL-Max Planck Centre for Computational Psychiatry and Ageing


Rune Asger Vestergaard Frandsen, MD, PhD

Rigshospitalet, Neurocentre
Department of Clinical Medicine


Salvatore Bertino, MD

University of Messina, Italy