Kristoffer Hougaard Madsen

Email

Tel.

+45 3862 2975

Position

Senior Researcher

Affiliations

DTU Compute, Technical University of Denmark

Research Interests

Research Groups

Computational Neuroimaging (Group Leader)
Acquisition Technology
fMRI
Motor Control

Curriculum Vitae

Education

2008

PhD, DTU Informatics, Technical University of Denmark

2004

MSc in Engineering (Applied physics), Technical University of Denmark

Employments

2016 - Present

Associate Professor, Cognitive Systems, DTU Compute, Technical University of Denmark

2009 - Present

Senior Researcher, DRCMR

2007 - 2009

Postdoc, DRCMR

2004 - 2004

Research assistant DRCMR (Torben E. Lund)

2002 - 2002

Research assistant, Florida Atlantic University (Larry S. Liebovitch)

Publications

Herz DM, Haagensen BN, Nielsen SH, Madsen KH, Løkkegaard A, Siebner HR (2016): Resting-state connectivity predicts levodopa-induced dyskinesias in Parkinson’s disease. Mov Disord.

Gelskov S V, Madsen KH, Ramsøy TZ, Siebner HR (2016): Aberrant neural signatures of decision-making: Pathological gamblers display cortico-striatal hypersensitivity to extreme gambles. Neuroimage 128:342–52.

Henningsson S, Madsen KH, Pinborg A, Heede M, Knudsen GM, Siebner HR, Frokjaer VG (2015): Role of emotional processing in depressive responses to sex-hormone manipulation: a pharmacological fMRI study. Transl Psychiatry 5

Gelskov S V, Henningsson S, Madsen KH, Siebner HR, Ramsøy TZ (2015): Amygdala signals subjective appetitiveness and aversiveness of mixed gambles. Cortex 66:81–90. 

Herz DM, Haagensen BN, Christensen MS, Madsen KH, Rowe JB, Løkkegaard A, Siebner HR (2015): Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans. Brain 138:1658–66.

Andersen M, Hanson LG, Madsen KH, Wezel J, Boer V, van der Velden T, van Osch MJP, Klomp D, Webb AG, Versluis MJ (2015): Measuring motion-induced B0 -fluctuations in the brain using field probes. Magn Reson Med.

Dogonowski A-M, Blinkenberg M, Paulson OB, Sellebjerg F, Sørensen PS, Siebner HR, Madsen KH (2015): Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis. J Neurol Neurosurg Psychiatry. 

K.H. Madsen, L. Ewald, H.S. Siebner, A. Thielscher. “Transcranial magnetic stimulation: An automated procedure to obtain coil-specific models for field calculations” Brain Stimulation 07/2015; doi: 10.1016/j.brs.2015.07.035

M. Andersen, L.G. Hanson, K.H. Madsen, J. Wezel, V. Boer, T. van der Velden, M.J.P. van Osch, A.G. Webb, M.J. Versluis. “Measuring motion-induced B0 -fluctuations in the brain using field probes” Magnetic Resonance in Medicine 06/2015; doi: 10.1002/mrm.25802

D.M. Herz, B.N. Haagensen, M.S. Christensen, K.H. Madsen, J.B. Rowe, A. Løkkegaard,H.R. Siebner. “Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans”. Brain 2015; doi: 10.1093/brain/awv096.

S.V. Gelskov, S. Henningsson, K.H. Madsen, H.R. Siebner,T.Z. Ramsøy. “Amygdala signals subjective appetitiveness and aversiveness of mixed gambles”. Cortex 2015; doi: 0.1016/j.cortex.2015.02.016.

D. M. Herz, B. N. Haagensen, M. S. Christensen, K. H. Madsen, J. B. Rowe, A. Løkkegaard, and H. R. Siebner, “The acute brain response to levodopa heralds dyskinesias in Parkinson disease”, Annals of Neurology, vol. 75, no. 6, pp. 829–36, 2014.

H. R. Laursen, H. R. Siebner, T. Haren, K. H. Madsen, R. Grønlund, O. Hulme, S. Henningsson. “Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy”. Frontiers in Behavioral Neuroscience. 2014, doi: 10.3389/fnbeh.2014.00423.

D. M. Herz, M.S. Christensen, N. Bruggemann, et al. “Motivational tuning of fronto-subthalamic connectivity facilitates control of action impulses.,” Journal of Neuroscience, 34(9):3210–7, 2014.

K. W. Andersen, K. H. Madsen, H. R. Siebner, M. N. Schmidt, M. Mørup, and L. K. Hansen, “Non-parametric Bayesian graph models reveal community structure in resting state fMRI.” Neuroimage, vol. 100C, pp. 301–315, 2014.

L. Gagnon, M. Vestergaard, K. H. Madsen, H. G. Karstensen, H. Siebner, N. Tommerup, R. Kupers, and M. Ptito, “Neural correlates of taste perception in congenital olfactory impairment.” Neuropsychologia, vol. 62C, pp. 297–305, 2014.

A.-M. Dogonowski, K. W. Andersen, K. H. Madsen, P. S. Sørensen, O. B. Paulson, M. Blinkenberg, and H. R. Siebner, “Multiple sclerosis impairs regional functional connectivity in the cerebellum.” NeuroImage Clinical, vol. 4, pp. 130–8, 2013.

I. Havsteen , K. H. Madsen, H. Christensen, A. Christensen, H. R. Siebner. “Diagnostic approach to functional recovery: functional magnetic resonance imaging after stroke” Frontiers of neurology and neuroscience, 32:9–25, 2013.

B. V Broberg, K. H. Madsen, N. Plath, C. K. Olsen, B. Y. Glenthøj, O. B. Paulson, B. Bjelke, and L. V Søgaard, “A schizophrenia rat model induced by early postnatal phencyclidine treatment and characterized by Magnetic Resonance Imaging” Behavioural brain research, vol. 250C, pp. 1–8, May 2013

J. P. M. van der Vegt, O. J. Hulme, S. Zittel, K. H. Madsen, M. M. Weiss, C. Buhmann, B. R. Bloem, A. Münchau, and H. R. Siebner, “Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson’s disease” Brain 2013, vol. 136, no. Pt 4, pp. 1192–203, 2013.

A. B. Nejad, K. H. Madsen, B. H. Ebdrup, H. R. Siebner, H. Rasmussen, B. Aggernæs, B. Y. Glenthøj, and W. F. C. Baaré, “Neural markers of negative symptom outcomes in distributed working memory brain activity of antipsychotic-naive schizophrenia patients” The international journal of neuropsychopharmacology, pp. 1–10, Nov. 2012.

A.-M. Dogonowski, H. R. Siebner, P. S. Sørensen, X. Wu, B. Biswal, O. B. Paulson, T. B. Dyrby, A. Skimminge, M. Blinkenberg, and K. H. Madsen, “Expanded functional coupling of subcortical nuclei with the motor resting-state network in multiple sclerosis” Multiple sclerosis, Sep. 2012.

A.-M. Dogonowski, H. R. Siebner, P. Soelberg Sørensen, O. B. Paulson, T. B. Dyrby, M. Blinkenberg, and K. H. Madsen, “Resting-state connectivity of pre-motor cortex reflects disability in multiple sclerosis” Acta Neurol. Scand., 2013.

P. M. Rasmussen, T. J. Abrahamsen, K. H. Madsen, and L. K. Hansen, “Nonlinear denoising and analysis of neuroimages with kernel principal component analysis and pre-image estimation” NeuroImage, vol. 60, no. 3, pp. 1807–18, Apr. 2012.

A. R. Lou, K. H. Madsen, H. O. Julian, P. B. Toft, T. W. Kjaer, O. B. Paulson, J. U. Prause, and H. R. Siebner, “Postoperative increase in grey matter volume in visual cortex after unilateral cataract surgery” Acta ophthalmologica, vol. i, pp. 1–8, Nov. 2011.

P. M. Rasmussen, L. K. Hansen, K. H. Madsen, N. W. Churchill, and S. C. Strother, “Model sparsity and brain pattern interpretation of classification models in neuroimaging” Pattern Recognition, 2011.

A. R. Lou, K. H. Madsen, O. B. Paulson, H. O. Julian, J. U. Prause, H. R. Siebner, and T. W. Kjaer, “Monocular Visual Deprivation Suppresses Excitability in Adult Human Visual Cortex.” Cerebral cortex, no. December, pp. 2876–2882, Apr. 2011.

P. M. Rasmussen, K. H. Madsen, T. E. Lund, and L. K. Hansen, “Visualization of nonlinear kernel models in neuroimaging by sensitivity maps” NeuroImage, vol. 55, no. 3, pp. 1120–31, Apr. 2011.

B. B. Biswal, M. Mennes, X.-N. Zuo et al., “Toward discovery science of human brain function” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 10, pp. 4734–9, Mar. 2010.

R. Kupers, D. R. Chebat, K. H. Madsen, O. B. Paulson, and M. Ptito, “Neural correlates of virtual route recognition in congenital blindness” Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 28, pp. 12716–21, Jul. 2010.

K. Korsholm, K. H. Madsen, J. L. Frederiksen, J. B. Rowe, and T. E. Lund, “Cortical neuroplasticity in patients recovering from acute optic neuritis” NeuroImage, vol. 42, no. 2, pp. 836–44, Aug. 2008.

D. J. Jacobsen, L. K. Hansen, and K. H. Madsen, “Bayesian model comparison in nonlinear BOLD fMRI hemodynamics” Neural computation, vol. 20, no. 3, pp. 738–55, Mar. 2008.

M. Mørup, L. K. Hansen, S. M. Arnfred, L.-H. Lim, and K. H. Madsen, “Shift-invariant multilinear decomposition of neuroimaging data” NeuroImage, vol. 42, no. 4, pp. 1439–50, Oct. 2008.

K. Korsholm, K. H. Madsen, J. L. Frederiksen, A. Skimminge, and T. E. Lund, “Recovery from optic neuritis: an ROI-based analysis of LGN and visual cortical areas” Brain: a journal of neurology, vol. 130, no. Pt 5, pp. 1244–53, May 2007.

K. Nielsen, K. H. Madsen, J. L. Frederiksen, A. M. Leffers, and T. E. Lund, “Functional magnetic resonance imaging corresponds to Humphrey perimetry in a patient with pituitary adenoma” Acta ophthalmologica Scandinavica, vol. 84, no. 2, pp. 267–8, Apr. 2006.

F. A. Nielsen, M. S. Christensen, K. H. Madsen, T. E. Lund, and L. K. Hansen, “fMRI neuroinformatics” IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society, vol. 25, no. 2, pp. 112–9, 2006.

T. E. Lund, K. H. Madsen, K. Sidaros, W.-L. Luo, and T. E. Nichols, “Non-white noise in fMRI: does modelling have an impact?” NeuroImage, vol. 29, no. 1, pp. 54–66, 2006.

A. Larsen, K. H. Madsen, T. E. Lund, and C. Bundesen, “Images of illusory motion in primary visual cortex” Journal of cognitive neuroscience, vol. 18, no. 7, pp. 1174–80, Jul. 2006.

M. S. Christensen, T. Z. Ramsøy, T. E. Lund, K. H. Madsen, and J. B. Rowe, “An fMRI study of the neural correlates of graded visual perception” NeuroImage, vol. 31, no. 4, pp. 1711–25, 2006.