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Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-(13) C]pyruvate

Asghar Butt S, Søgaard LV, Ardenkjaer-Larsen JH, Lauritzen MH, Engelholm LH, Paulson OB, Mirza AO, Holck S, Magnusson P and Akeson P

2015

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To use dynamic magnetic resonance spectroscopy (MRS) of hyperpolarized (13) C-pyruvate to follow the progress over time in vivo of breast cancer metabolism in the MMTV-PymT model, and to follow the response to the anti-estrogen drug tamoxifen.

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