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Corpus callosum atrophy in patients with mild Alzheimer's disease

Frederiksen KS, Garde E, Skimminge A, Ryberg C, Rostrup E, Baaré WFC, Siebner HR, Hejl A, Leffers A and Waldemar G

2011

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Several studies have found atrophy of the corpus callosum (CC) in patients with Alzheimer’s disease (AD). However, it remains unclear whether callosal atrophy is already present in the early stages of AD, and to what extent it may be associated with other structural changes in the brain, such as age-related white matter changes (ARWMC) and progression of the disease.

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