DRCMR

Contact:
Danish Research Centre for Magnetic Resonance
Copenhagen University Hospital Hvidovre
Kettegård Allé 30
DK-2650 Hvidovre




E-mail:
norbertb#drcmr.dk

Current position:

Guest researcher at DRCMR (July 2011 - now)

Education, Training:

M.D., Medical Faculty, University of Lübeck, 2005

Habilitation, Priv.-Doz. (postdoctoral thesis), Medical Faculty, University of Lübeck, 2012

Research Fellow in Neurogenetics, Section of Clinical and Molecular Neurogenetics, University of Lübeck, Germany, June 2005 - June 2011

Research and Clinical Fellow in Movement Disorders, Department of Neurology, University of Lübeck, Germany, June 2005 - June 2011

Residency, Neurology, University of Lübeck, June 2005 - Dec. 2010; Psychiatry, University of Lübeck, Jan. 2011 - June 2011

Research group (DRCMR):

ContAct

Current areas of research interest:

• Sensorimotor control of actions and movement disorders (ContAct)
• Multimodal in vivo mapping (fMRI, TMS) of human brain networks

Other research interests:

• Genetics of movement disorders
• Transcranial sonography

Selected publications:

Brüggemann N, Kock N, Lohmann K, König IR, Rakovic A, Hagenah J, Schmidt A, Ziegler A, Jabusch HC, Siebner H, Altenmüller E, Münchau A, Klein C (2009) The D216H variant in the DYT1 gene - a susceptibility factor for dystonia in familial cases? Neurology 72(16):1441-3.

Djarmati A, Schneider SA, Lohmann K, Winkler S, Pawlack H, Hagenah J, Brüggemann N, Zittel S, Fuchs T, Rakovic A, Schmidt A, Jabusch HC, Wilcox R, Kostic VS, Siebner H, Altenmüller E, Münchau A, Ozelius LJ, Klein C (2009) Mutations in THAP (DYT6) and generalized dystonia with prominent spasmodic dysphonia: a genetic screening study. Lancet Neurol 8(5):447-52. (read the abstract/article)

Brüggemann N, Hagenah J, Reetz K, Schmidt A, Kasten M, Buchmann I, Eckerle S, Bähre M, Münchau A, Djarmati A, van der Vegt J, Siebner H, Binkofski F, Ramirez A, Behrens MI, Klein C (2010) Recessively inherited parkinsonism: effect of ATP13A2 mutations on the clinical and neuroimaging phenotype. Arch Neurol 67(11):1357-63. (read the abstract/article)

Eggers C, Schmidt A, Hagenah J, Brüggemann N, Klein JC, Tadic V, Kertelge L, Kasten M, Binkofski F, Siebner H, Neumaier B, Fink GR, Hilker R, Klein C (2010) Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit. Neurology 74(22):1798-805. (read the abstract/article)

Brüggemann N, Klein C (2010) Genetics of Primary Torsion Dystonia. Curr Neurol Neurosci Rep 10(3):199-206. Review. (read the abstract/article)

Brüggemann N, van der Vegt J, Klein C, Siebner HR (2010) Imaging of genetic aspects of Parkinson's disease. Nervenarzt 81(10):1196-1203. (Review, in German). (read the abstract/article)

Hagenah J, König IR, Kötter C, Seidel G, Klein C, Brüggemann N (2010) Basal ganglia hyperechogenicity does not distinguish between patients with primary dystonia and healthy individuals. J Neurol 258(4):590-5. (read the abstract/article)

Hagenah J, König IR, Sperner J, Wessel L, Seidel G, Condefer K, Saunders-Pullman, Klein C, Brüggemann N (2010) Life-long increase of substantia nigra hyperechogenicity in transcranial sonography. Neuroimage 51(1):28-32. (read the abstract/article)

Reetz K, Tadic V, Kasten M, Brüggemann N, Schmidt A, Hagenah J, Pramstaller PP, Ramirez A, Behrens MI, Siebner HR, Klein C, Binkofski F (2010) Structural imaging in the presymptomatic stage of genetically determined parkinsonism. Neurobiol Dis 39(3):402-8. (read the abstract/article)

Brüggemann N, Hagenah J, Stanley K, Klein C, Wang C, Raymond D, Ozelius L, Bressman S, Saunders-Pullman R (2011) Substantia nigra hyperechogenicity with LRRK2 G2019S mutations. Mov Disord 26(5):885-8. (read the abstract/article)