It is with deep regrets that we have to acknowledge that our dear colleague Lise Vejby Søgaard passed away, February 2014.


Danish Research Centre for Magnetic Resonance
Copenhagen University Hospital Hvidovre
Kettegård Allé 30
DK-2650 Hvidovre


Current position:
Senior researcher at DRCMR
Preclinical research group leader at DRCMR

M.Sc. in Physics, from University of Aarhus
Ph.d. from Institute of Physics and Astronomy, University of Aarhus

Research groups:
Preclinical MRI research group
Hyperpolarized MRI research group
Diffusion imaging group
Physics & acquisition research group

Main research interests:
Preclinical MRI with the aim of develop and optimize methods to characterize healthy and diseased tissue.
Metabolic imaging and spectroscopy using hyperpolarized carbon-13 labelled substances.
Hyperpolarized helium-3 lung imaging to monitor disease progression in COPD (chronic obstructive pulmonary disease).

Other research interest(s):
Microstructural characterisation of tissue using diffusion (and other) methods.

Academic activities:
2007- Research Group Leader at DRCMR (preclinical research group, hyperpolarization group)
2007-2011 Scientist in charge for the Copenhagen partner of PHeLINet (Polarized Helium Lung Imaging Network) supported by the European Commission (FP6)
2003-2009 Internal coordinator of the DRCMR Reader Centre
2005- Member of Elektrocensorkorpset. External examiner (censor) at MR courses at University of Aarhus.
Regular teaching of diffusion MRI and MR physics at local and external courses
Supervisor or co-supervisor for Phd-students and Masters students

Selected publications:

Dyrby TB, Søgaard LV, Hall MG, Ptito M, Alexander DC
Contrast and stability of the axon diameter index from microstructure imaging with diffusion MRI.
Magnetic Resonance in Medicine 2012 doi: 10.1002/mrm.24501. [Epub ahead of print]

Butt SA, Søgaard LV, Magnusson P, Lauritzen M, Laustsen C, Åkeson P, Ardenkjær-Larsen JH
Imaging cerebral 2-ketoisocaproate metabolism with hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging.
Journal of Cerebral Blood Flow&Metabolism 2012;32(8):1508-14

Dyrby TB, Baaré WF, Alexander DC, Jelsing J, Garde E, Søgaard LV
An ex vivo imaging pipeline for producing high-quality and high-resolution diffusion weighted imaging datasets,
Human brain mapping. 2011;32(4):544-63

Skjolding AD, Rowland IJ, Søgaard LV, Praetorius J, Penkowa M, Juhler M
Hydrocephalus induces dynamic spatiotemporal regulation of aquaporin-4 expression in the rat brain.
Cerebrospinal fluid research. 2010;7:20.

Sorensen PS, Mellgren SI, Svenningsson A, Elovaara I, Frederiksen JL, Beiske AG, Myhr KM, Søgaard LV, Olsen IC, Sandberg-Wollheim M
NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial.
The Lancet Neurology. 2009;8(6):519-529.

Stavngaard T, Søgaard LV, Batz M, Schreiber LM, Dirksen A
Progression of emphysema evaluated by MRI using hyperpolarized (3)He (HP (3)He) measurements in patients with alpha-1-antitrypsin (A1AT) deficiency compared with CT and lung function tests.
Acta radiologica. 2009;50(9):1019-26.

Beek EJR van, Dahmen AM, Stavngaard T, Gast KK, Heussel CP, Krummenauer F, Schmiedeskamp J, Wild JM, Søgaard LV, Morbach AE, Schreiber LM, Kauczor HU
Hyperpolarised 3He MRI versus HRCT in COPD and normal volunteers: PHIL trial.
The European respiratory journal. 2009;34(6):1311-21.

Madsen KS, Holm DA, Søgaard LV, Rowland IJ
Effect of paramagnetic manganese cations on (1) H MRS of the brain.
NMR in Biomedicine. 2008;21(10):1087-1093.

Brandt CT, Simonsen H, Liptrot M, Søgaard LV, Lundgren JD, Ostergaard C, Frimodt-Møller N, Rowland IJ
In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging.
BMC medical imaging. 2008;81.

Dyrby TB, Sogaard LV, Parker GJ, Alexander DC, Lind NM, Baare WF, Hay-Schmidt A, Eriksen N, Pakkenberg B, Paulson OB, Jelsing J
Validation of in vitro probabilistic tractography.
Neuroimage 2007;37(4):1267-1277.

Stavngaard T, Søgaard LV, Mortensen J, Hanson LG, Schmiedeskamp J, Berthelsen AK, Dirksen A
Hyperpolarized 3He MRI and 81mKr SPECT in chronic obstructive pulmonary disease.
European journal of nuclear medicine and molecular imaging. 2005;32(4):448-57.

Schreiber WG, Morbach AE, Stavngaard T, Gast KK, Herweling A, Søgaard LV, Windirsch M, Schmiedeskamp J, Heussel CP, Kauczor HU
Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3.
Respiratory physiology & neurobiology. 2005;148(1-2):23-42.

Curriculum vitae:
Senior researcher
Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre
2001 - Now

Assistant Research Professor
The Ørsted Laboratory, Niels Bohr Institute, University of Copenhagen.
1999 - 2001

Risø National Laboratory
1997 - 1998

Assistant Professor
Dept. of Physics and Astronomy, University of Aarhus

PhD in physics
Title of thesis: Electron-ion collision studies at ASTRID
Dept. of Physics and Astronomy, University of Aarhus