Damian Herz Contact:
Danish Research Centre for Magnetic Resonance (DRCMR)
Copenhagen University Hospital Hvidovre, Section 714
Kettegård Allé 30
DK-2650 Hvidovre
Denmark
Email: damianh#drcmr.dk

Current position:
Resident in Neurology at University Hospital Copenhagen

Research groups:
ContAct

Main research interests:
The human sensorimotor system consists of complex networks of spatially remote neural regions. Communication between these regions enables us to flexibly control our actions. Patients with Parkinson’s disease are no longer able to properly control actions. The neural mechanism underlying impaired motor control in Parkinson’s disease, however, remains largely unknown.
In my studies, I wish to investigate whether abnormal neural communication underlies impaired motor control in patients with Parkinson’s disease. To address this question I use functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), which allow characterization of neural communication with a high spatial and temporal resolution, respectively. Additionally, I use diffusion-weighted imaging (DWI) and transcranial magnetic stimulation (TMS) to investigate structural and functional connectivity in the human brain.


Education:

2014 -: Resident in Neurology, University Hospital Copenhagen, Denmark

2010 - 2014: PhD in Neuroscience, DRCMR, University of Copenhagen, Denmark

2003 - 2010: Study of Medicine, University of Cologne, Germany

Awards and sholarships:

2014: Travel grant from Lundbeck Foundation

2013: Young researcher award of the Danish Parkinson Society

2012: Research grant from Hvidovre Hospital

2008 – 2009: Research grant "Köln Fortune"

2006 - 2010: Educational grant from German National Academic Foundation ("Studienstiftung des Deutschen Volkes")

Publications:

Herz, D.M., Haagensen, B.N., Christensen, M.S., Madsen, K.H., Rowe, J.B., Løkkegaard, A., Siebner, H.R. (2014) The acute brain response to levodopa heralds dyskinesias in Parkinson disease. Annals of Neurology. Epub ahead of print.

Herz, D.M., Christensen, M.S., Bruggemann, N., Hulme, O.J., Ridderinkhof, K.R., Madsen, K.H., Siebner, H.R. (2014) Motivational tuning of fronto-subthalamic connectivity facilitates control of action impulses. Journal of Neuroscience 34:3210-3217

Herz, D.M., Siebner H.R., Hulme, O.J., Florin, E., Christensen, M.S., Timmermann, L. (2013) Levodopa reinstates connectivity from prefrontal to premotor cortex during externally-paced movement in Parkinson's disease. NeuroImage Epub ahead of print.

Herz, D.M., Florin, E., Christensen, M.S., Reck, C., Barbe, M.T., Tscheuschler, M.K., Tittgemeyer, M., Siebner, H.R., Timmermann, L. (2013) Dopamine replacement modulates oscillatory coupling between premotor and motor cortical areas in Parkinson’s disease. Cerebral Cortex Epub ahead of print.

Herz, D.M., Eickhoff, S.B., Lokkegaard, A., Siebner, H.R. (2013) Functional Neuroimaging of Motor Control in Parkinson’s Disease: A Meta-analysis. Human Brain Mapping Epub ahead of print

Herz, D.M., Christensen, M.S., Reck, C., Florin, E., Barbe, M.T. Stahlhut, C., Pauls, K.A.M., Tittgemeyer, M., Siebner, H.R., Timmermann, L. (2012): Task-specific modulation of effective connectivity during two simple unimanual motor tasks: a 122-channel EEG study. NeuroImage 59: 3187-3193

Siebner, H.R. & Herz, D.M. (2013): fMRI in Parkinson’s Disease. In Ulmer, S. and Jansen O. (ed): fMRI: Basics and Clinical Applications, Second Edition 2013, Springer, Heidelberg.

Rosso, C., Valabregue, R., Arbizu, C., Ferrieux, S., Vargas, P., Humbert, F., Attal, Y., Messé, A., Zavanone, C., Meunier, S., Cohen, L., Delmaire, C., Thielscher, A., Herz, D.M., Siebner, H.R., Samson, Y., Lehéricy, S. (2014): Connectivity between right inferior frontal gyrus and supplementary motor area predicts aftereffects of right frontal cathodal tDCS on picture naming speed. Brain Stimulation 7:122-129