Anouk Marsman



+45 3862 6446



Personal webpage

Research Interests

I am leading MR spectroscopy research at DRCMR and as such I initiated several neuroscientific studies on brain chemistry in health and disease. I am heading studies on normal ageing and neurodegenerative diseases, schizophrenia, and development of novel techniques. I am also a key player in collaborative and international consortium studies on e.g. migraine, diabetes and ultra-high field MRI method standardisation, where I am responsible for MR spectroscopy.

Research Groups

Ultra-High Field MR

Curriculum Vitae



PhD Neuroscience, Utrecht University, The Netherlands


MSc Biology (Cum Laude), University of Groningen, The Netherlands


2015 - Present

Postdoc, DRCMR

2013 - 2015

Russell H. Morgan Department of Radiology & Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA

2008 - 2013

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands

Full CV


Video Pitch: Presentation 

Hansen, A. L., Boer, V. O., Andersen, M., Petersen, E. T. & Marsman, A.
Reproducible in vivo assessment of GABA and GSH using MR Spectroscopy.
1 p., 2018.

Marsman, A., Boer, V. O., Andersen, M. & Petersen, E. T.
Real-time frequency and motion corrected Hadamard encoded spectral editing (CHASE).

Magnusson, O. P., Boer, V. O., Marsman, A., Lundell, H. M. H., Hanson, L. G. & Petersen, E. T.
GABA-edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T.

Hansen, A. L., Marsman, A., Madsen, C. D., Garde, E., Mortensen, E. L., Rasmussen, L. J., Petersen, E. T. & Siebner, H. R.
Mitochondrial and Immunological Effects on the Interplay Between Brain and Body Ageing.

Andersen, M., Boer, V. O., Marsman, A. & Petersen, E. T.
A generalized prospective motion correction framework for improved spectroscopy, structural and angiographic imaging.

Bhogal AA, Schür RR, Houtepen LC, Van de Bank B, Boer VO, Marsman A, Barker PB, Scheenen T, Wijnen JP, Vinkers CH, Klomp DWJ. 1H-MRS processing parameters affect metabolite quantification: the urgent need for uniform and transparent standardization. NMR Biomed, 2017, accepted.

Marsman A, Mandl RCW, Klomp DWJ, Cahn W, Kahn RS, Luijten PR, Hulshoff Pol HE. Intelligence and brain efficiency: investigating the association between working memory performance, glutamate and GABA. Frontiers in Psychiatry, 2017, 8:154. doi: 10.3389/fpsyt.2017.00154

Posporelis S, Coughlin J, Marsman A, Pradhan S, Tanaka T, Wang H, Varvaris M, Ward R, Higgs C, Edwards JA, Ford CN, Kim PK, Lloyd AM, Edden RA, Schretlen D, Cascella NG, Barker PB, Sawa A. Decoupling of brain temperature and glutamate in recent-onset of schizophrenia: a 7 Tesla 1H-MRS study. Biol Psychiatry CNNI, 2017, in press. doi:

De Jonge JC, Vinkers CH, Hulshoff Pol HE, Marsman A. Neurobiological mechanisms of GABA in schizophrenia: a comprehensive review of postmortem and in vivo studies. Frontiers in Psychiatry, 2017, 8:118. doi: 10.3389/fpsyt.2017.00118

Marsman A, Boer VO, Luijten PR, Hulshoff Pol HE, Klomp DWJ, Mandl RCW. Detection of glutamate alterations in the human brain using 1H-MRS: Comparison of STEAM and sLASER at 7T. Frontiers in Psychiatry, 2017, 8:60. doi: 10.3389/fpsyt.2017.00060

Coughlin JM, Tanaka T, Marsman A, Wang H, Bonekamp S, Higgs C, Kim PK, Edwards JA, Varvaris M, Wang H, Posporelis S, Ma S, Tsujimura T, Edden RA, Pomper MG, Sedlak T, Do K, Schretlen D, Cascella NG, Barker PB, Sawa A. Decoupling of N-acetyl aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia. Curr Mol Med, 2015, 15(2):176-183. doi: 10.2174/1566524015666150303104811

Marsman A. Magnetic resonance spectroscopy, In: Imaging of the brain (Dutch); Hulshoff Pol HE, Aleman A (eds.), Utrecht, The Netherlands, 2015: 23-32.

Marsman A, Mandl RCW, Klomp DWJ, Bohlken MM, Boer VO, Andreychenko A, Cahn W, Kahn RS, Luijten PR, Hulshoff Pol HE. GABA and glutamate in schizophrenia: a 7T 1H-MRS study. Neuroimage Clin, 2014, 6:398-407. doi: 10.1016/j.nicl.2014.10.005

Marsman A, Mandl RCW, Van den Heuvel MP, Boer VO, Wijnen JP, Klomp DWJ, Luijten PR, Hulshoff Pol HE. Glutamate changes in healthy young adulthood. Eur Neuropsychopharmacol, 2013, 23(11):1484-1490. doi: 10.1016/j.euroneuro.2012.11.003

Marsman A, Van den Heuvel MP, Hulshoff Pol HE, Glutamatergic neurotransmission in schizophrenia, In: Handbook of schizophrenia (Dutch); Cahn W, Krabbendam L, Myin-Germeys I, Bruggeman R, De Haan L (eds.), Utrecht, The Netherlands, 2011: 305-312.

Marsman A, Van den Heuvel MP, Klomp DWJ, Kahn RS, Luijten PR, Hulshoff Pol HE. Glutamate in schizophrenia: a focused review and meta-analysis of 1H-MRS studies. Schizophr Bull, 2013, 39(1):120-129. doi: 10.1093/schbul/sbr069