DRCMR

Overall research areas
Sequences and image reconstruction
Field inhomogeneity and artifacts
Multi-modal data acquisition
Spectroscopy and spectroscopic imaging

Lars G. Hanson
Group leader
DRCMR, DTU Elektro

Spectroscopic imaging
EEG-fMRI recording
Fields, artifacts & sequences

Lise Vejby Søgaard
DRCMR

Hyperpolarized Helium MRI
Hyperpolarized Carbon MRI

Peter Magnusson
DRCMR

Hyperpolarized Helium MRI
Hyperpolarized Carbon MRI

Kristoffer H. Madsen
DRCMR, DTU Informatics

fMRI analysis

Arnold Skimminge
DRCMR, DTU Informatics

Multi-modal imaging
Image artifacts/corrections

Mads Andersen
DRCMR

Fields and motion

Objectives:
The members of the “MR physics and acquisition group” at the DRCMR work largely independently, or in other research groups, but meet regularly to discuss acquisition methodology. They implement sequences and protocols, and do research improving MR scanning, e.g. with respect to speed, sensitivity or specificity. The employed methods range from fundamental physics to advanced data processing techniques needed to extract important physiological parameters from the measurements. The targets of the development include imaging, spectroscopy, and multi-modal acquisition.

The group also provides education in MRI physics and techniques at the DRCMR, the DTU and elsewhere. Educational material and software developed for this was made freely available, and is now used widely internationally.

Group description:
The group members have technical backgrounds, e.g. in physics, mathematics and engineering.

Strong external collaborations are established. Most notably, there are strong ties to departments at the Technical University of Denmark (DTU) via Kristoffer H. Madsen and Arnold Skimminge (DTU Informatics) and via double-appointment of Lars G. Hanson (DRCMR and Biomedical Engineering/Medicine&Technology at DTU Elektro).

Most group members are also associated with other DRCMR groups, focusing more on the applications which provide the ultimate incentives for doing methodological development.

Resources:
Data acquisition is done with MR scanners, EEG, ECG and other physiological monitoring equipment. The DRCMR has a well-equipped electronics workshop.

Selected publications:

Andersen, M; Hanson LG. A phatom-based validation framework for EEG-fMRI acquisition methods, Proceedings of the ESMRMB, 2012.

Vestergaard, M; Schulz J; Turner, R; Hanson LG. Motion tracking from gradient induced signals in electrode recordings. Proceedings of the ESMRMB, 368, 2011.

de Nijs R;Miranda MJ;Hansen LK;Hanson LG. Motion correction of single-voxel spectroscopy by independent component analysis applied to spectra from nonanesthetized pediatric subjects.
Magn Reson Med 2009, 62(5), 1147-1154.
WebSearch

Søgaard LV;Dorniok T;Hengstenberg F;Karpuk S;Vestbo J;Åkeson P;Magnusson P.
Compressed Sensing for Hyperpolarized 3He 3D ADC Measurements. Oral presentation.
Proc Intl Soc Magn Reson Med 2009, 7.

Hanson LG. Is quantum mechanics necessary for understanding magnetic resonance?
Concepts in Magnetic Resonance Part A 2008, 32A(5), 329-340.
PDF | WebSearch

Hanson LG. A graphical simulator for teaching basic and advanced MR imaging techniques.
Radiographics 2007, 27(6), e27.
PDF | WebSearch

Hanson LG;Lund TE;Hanson CG. Encoding of electrophysiology and other signals in MR images.
J Magn Reson Imaging 2007, 25(5), 1059-1066.
PDF | WebSearch

Hanson LG;Lund TE;Hanson CG. Encoding and transmission of signals as RF signals for detection using an MR apparatus. WO/2005/116676, PCT/DK2005/000343 2005.
PDF | WebSearch

Andersen IK;Szymkowiak A;Rasmussen CE;Hanson LG;Marstrand JR;Larsson HB;Hansen LK. Perfusion quantification using Gaussian process deconvolution.
Magn Reson Med 2002, 48(2), 351-361.
WebSearch

Hanson LG;Adalsteinsson E;Pfefferbaum A;Spielman DM. Optimal voxel size for measuring global gray and white matter proton metabolite concentrations using chemical shift imaging.
Magn Reson Med 2000, 44(1), 10-18.
PDF | WebSearch

Hanson LG;Schaumburg K;Paulson OB. Reconstruction strategy for echo planar spectroscopy and its application to partially undersampled imaging. Magn Reson Med 2000, 44(3), 412-417.
PDF | WebSearch

Collaborators:
DTU Biomedical Engineering, Technical University of Denmark, Lyngby (DTU Electro)
DTU Informatics, Technical University of Denmark, Lyngby (DTU Informatics)
Max Planck Institute for Human Cognitive and Brain Science, Leipzig, Germany
Department of Medical Physics, University of Freiburg, Germany
Niels Bohr Instituttet, University of Copenhagen, Denmark (NBI)
The Copenhagen Muscle Research Centre, University of Copenhagen, Denmark (CMRC)
School of Physiotherapy and Exercise Science, Griffith University, Australia